Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3486141..3486772 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JET59_RS16415 Protein ID WP_099064654.1
Coordinates 3486141..3486539 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JET59_RS16420 Protein ID WP_085117342.1
Coordinates 3486539..3486772 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS16390 (JET59_016390) 3481712..3482098 + 387 WP_219016530.1 type II toxin-antitoxin system RelE/ParE family toxin -
JET59_RS16395 (JET59_016395) 3482079..3482381 + 303 WP_006321467.1 helix-turn-helix domain-containing protein -
JET59_RS16400 (JET59_016400) 3482385..3482789 - 405 WP_099064651.1 flagellar protein FlhE -
JET59_RS16405 (JET59_016405) 3482789..3484867 - 2079 WP_112349619.1 flagellar biosynthesis protein FlhA -
JET59_RS16410 (JET59_016410) 3484860..3486011 - 1152 WP_099064653.1 flagellar biosynthesis protein FlhB -
JET59_RS16415 (JET59_016415) 3486141..3486539 - 399 WP_099064654.1 type II toxin-antitoxin system VapC family toxin Toxin
JET59_RS16420 (JET59_016420) 3486539..3486772 - 234 WP_085117342.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JET59_RS16425 (JET59_016425) 3486897..3487541 - 645 WP_099064655.1 protein phosphatase CheZ -
JET59_RS16430 (JET59_016430) 3487552..3487941 - 390 WP_037418944.1 chemotaxis response regulator CheY -
JET59_RS16435 (JET59_016435) 3488155..3489204 - 1050 WP_099064657.1 chemotaxis response regulator protein-glutamate methylesterase -
JET59_RS16440 (JET59_016440) 3489204..3490076 - 873 WP_026142427.1 protein-glutamate O-methyltransferase CheR -
JET59_RS16445 (JET59_016445) 3490105..3491730 - 1626 WP_219016534.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15068.36 Da        Isoelectric Point: 8.1127

>T270006 WP_099064654.1 NZ_CP117168:c3486539-3486141 [Serratia proteamaculans]
MFSHMLDTNIVIYVIKRRPLEVLQRFNQHAGKMVISSVTYAELIHGVEKSMRPTENARVIDDFVSRLEILDYTAKAAAHY
GNIRACLERQGTPIGINDLHIAGHARSEGLVLVTNNLREFERVDGLRLQNWL

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8871.79 Da        Isoelectric Point: 4.5535

>AT270006 WP_085117342.1 NZ_CP117168:c3486772-3486539 [Serratia proteamaculans]
MTLGSVFTNNRTQAVRLPAEVRFPDSVSKVSVRVVGKERILSPVENTWDSFFCTDNHVSDDFLSERADQYQSEREEF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References