Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 999414..1000104 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag JET59_RS04680 Protein ID WP_099064956.1
Coordinates 999730..1000104 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag JET59_RS04675 Protein ID WP_207976426.1
Coordinates 999414..999743 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS04655 (JET59_004655) 995312..996772 - 1461 WP_207976435.1 NCS1 family nucleobase:cation symporter-1 -
JET59_RS04660 (JET59_004660) 996939..997688 + 750 WP_219015452.1 GntR family transcriptional regulator -
JET59_RS04665 (JET59_004665) 997685..998428 + 744 WP_219015453.1 aspartate/glutamate racemase family protein -
JET59_RS04670 (JET59_004670) 998448..999386 + 939 WP_219015454.1 allantoinase PuuE -
JET59_RS04675 (JET59_004675) 999414..999743 - 330 WP_207976426.1 helix-turn-helix transcriptional regulator Antitoxin
JET59_RS04680 (JET59_004680) 999730..1000104 - 375 WP_099064956.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JET59_RS04685 (JET59_004685) 1000205..1002442 - 2238 WP_099064955.1 TonB-dependent siderophore receptor -
JET59_RS04690 (JET59_004690) 1002479..1003807 - 1329 WP_219015455.1 lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(16-95)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13828.04 Da        Isoelectric Point: 9.7052

>T269996 WP_099064956.1 NZ_CP117168:c1000104-999730 [Serratia proteamaculans]
MDTHRVRQLVWIASSKKDLLSLPDEVIKSVGYSLHCAQAGLIPPGVKALKGFQGAGVLEVVEDHDSNTYRAVYTLRFEDA
VFVLHCFQKKSKTGVATPKADIELIKSRLNRAKQVYEDMKNGKI

Download         Length: 375 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12169.89 Da        Isoelectric Point: 4.7969

>AT269996 WP_207976426.1 NZ_CP117168:c999743-999414 [Serratia proteamaculans]
MAKYDENDFELGSDNIFADLNLPDADNLQLKADLAIQIISTIKQLGLNQAEAGKRMNLPQARVSALYNGKFFNMSEKKLM
DCLNRLGYDIEIVVRPSQDPVGHRTLSVA

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References