Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 906632..908315 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag JET59_RS04175 Protein ID WP_219015426.1
Coordinates 907398..908315 (+) Length 306 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag JET59_RS04170 Protein ID WP_219015425.1
Coordinates 906632..907405 (+) Length 258 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS04160 (JET59_004160) 902634..903632 + 999 WP_099062789.1 RNA polymerase sigma factor RpoS -
JET59_RS04165 (JET59_004165) 903713..906268 - 2556 WP_099062790.1 DNA mismatch repair protein MutS -
JET59_RS04170 (JET59_004170) 906632..907405 + 774 WP_219015425.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
JET59_RS04175 (JET59_004175) 907398..908315 + 918 WP_219015426.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
JET59_RS04180 (JET59_004180) 908472..909482 - 1011 WP_260329091.1 hypothetical protein -
JET59_RS04185 (JET59_004185) 909518..910489 - 972 WP_219015444.1 aldo/keto reductase -
JET59_RS04190 (JET59_004190) 910539..911342 - 804 WP_219015427.1 glucose 1-dehydrogenase -
JET59_RS04195 (JET59_004195) 911449..912366 + 918 WP_219015428.1 LysR family transcriptional regulator -
JET59_RS04200 (JET59_004200) 912860..913177 + 318 WP_219015445.1 PTS sugar transporter subunit IIB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-279)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-93)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 34642.89 Da        Isoelectric Point: 5.0738

>T269995 WP_219015426.1 NZ_CP117168:907398-908315 [Serratia proteamaculans]
MDKHSPYYRQVALLLSTLPVVASERCFALKGGTAINLFVRDFPRLSVDIDLAYIPLENRDVALPNVRAALTRIAEILQQQ
AGISAVLQTNNSDEMRIVVYSQQAQIKIEVSPVARGTLYPSEERDVVEAVENEFGFANIQVVSLADLYGGKLCAALDRQH
PRDFYDVKMLLETQGIDRQIFNGFITYLLGHPRPLSEVLNPRWKNISELYANEFNGMTFDMVSLEELNAIPELMLTALKV
QFTQRDCDFLMSFKRGEPDWSLAPENQIQYLPAVRWKLQNIGRMPKEKHIQALVKLEETLAGWIG

Download         Length: 918 bp

Antitoxin


Download         Length: 258 a.a.        Molecular weight: 28991.34 Da        Isoelectric Point: 9.8515

>AT269995 WP_219015425.1 NZ_CP117168:906632-907405 [Serratia proteamaculans]
MSSKLNWLLQNTAPGSLVLQSWLTKNGISPSLANKYMHSDWLQKLRAGVYVRSGREPQWSDAVLCLQHQLGVSVHLAGLT
SLTYQGRSHYLQLTRQVIWLCVENKASLPKWFKEFPNVEWLLLSNQKLNMHDGKYLTEVEIKGERLKASVPELAAYEVAN
AVPGSLSFEHAAELFQGLVNLSPRKVEALLQSSRAVQTNRLYLFLADHYVHAWVKRIDKTNIDLGAGKRQIVSGGKLDQK
YQITVPESFVSKEISHG

Download         Length: 774 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References