Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 68226..68761 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JET59_RS00305 Protein ID WP_099062250.1
Coordinates 68486..68761 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JET59_RS00300 Protein ID WP_099062251.1
Coordinates 68226..68486 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS00280 (JET59_000280) 63558..64205 + 648 WP_219015060.1 DcrB-related protein -
JET59_RS00285 (JET59_000285) 64240..64845 + 606 WP_085115218.1 glutathione S-transferase -
JET59_RS00290 (JET59_000290) 64913..66304 + 1392 WP_219015061.1 L-seryl-tRNA(Sec) selenium transferase -
JET59_RS00295 (JET59_000295) 66301..68142 + 1842 WP_219015062.1 selenocysteine-specific translation elongation factor -
JET59_RS00300 (JET59_000300) 68226..68486 + 261 WP_099062251.1 ribbon-helix-helix domain-containing protein Antitoxin
JET59_RS00305 (JET59_000305) 68486..68761 + 276 WP_099062250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JET59_RS00310 (JET59_000310) 68836..70083 - 1248 WP_219015063.1 MFS transporter -
JET59_RS00315 (JET59_000315) 70303..71295 + 993 WP_219015064.1 acyltransferase -
JET59_RS00320 (JET59_000320) 71290..72213 - 924 WP_099062247.1 DJ-1/PfpI family protein -
JET59_RS00325 (JET59_000325) 72216..72767 - 552 WP_219015065.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10804.61 Da        Isoelectric Point: 10.0859

>T269994 WP_099062250.1 NZ_CP117168:68486-68761 [Serratia proteamaculans]
MELKWTSKALSDLARLFEFLALANRTAAAHMMQALVAAPKVLRDNPRIGERLDEFLPQEVRRILIGHYEMRYQLHSSTIY
ILRIWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9739.15 Da        Isoelectric Point: 4.8782

>AT269994 WP_099062251.1 NZ_CP117168:68226-68486 [Serratia proteamaculans]
MNTKVITAHVPLPLADKVDEMAAKLERSRGWIVKQALAAWLDQEEERRRLTLEALADVEQKNIIDHESVEAWAASLDSEK
PLPVPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References