Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 5727703..5728289 Replicon chromosome
Accession NZ_CP117167
Organism Mucilaginibacter jinjuensis strain KACC 16571

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PQO05_RS24760 Protein ID WP_273630152.1
Coordinates 5727703..5728086 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PQO05_RS24765 Protein ID WP_273630153.1
Coordinates 5728086..5728289 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQO05_RS24735 (PQO05_24735) 5722857..5724548 - 1692 WP_273630147.1 glycosyltransferase family 39 protein -
PQO05_RS24740 (PQO05_24740) 5724690..5724926 + 237 WP_273630148.1 hypothetical protein -
PQO05_RS24745 (PQO05_24745) 5725058..5725474 + 417 WP_273630149.1 hypothetical protein -
PQO05_RS24750 (PQO05_24750) 5725629..5726900 - 1272 WP_273630150.1 serine--tRNA ligase -
PQO05_RS24755 (PQO05_24755) 5727028..5727702 + 675 WP_273630151.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
PQO05_RS24760 (PQO05_24760) 5727703..5728086 - 384 WP_273630152.1 type II toxin-antitoxin system VapC family toxin Toxin
PQO05_RS24765 (PQO05_24765) 5728086..5728289 - 204 WP_273630153.1 DUF2281 domain-containing protein Antitoxin
PQO05_RS24770 (PQO05_24770) 5728349..5729950 + 1602 WP_273630154.1 apolipoprotein N-acyltransferase -
PQO05_RS24775 (PQO05_24775) 5730020..5730871 - 852 WP_273630155.1 N-acetylglucosamine kinase -
PQO05_RS24780 (PQO05_24780) 5730868..5731251 - 384 WP_174314849.1 response regulator -
PQO05_RS24785 (PQO05_24785) 5731302..5732621 - 1320 WP_273630156.1 TolC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(4-126)

Antitoxin

Domain of unknown function DUF2281

(6-66)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14813.20 Da        Isoelectric Point: 4.9320

>T269993 WP_273630152.1 NZ_CP117167:c5728086-5727703 [Mucilaginibacter jinjuensis]
MDYLLDTHILLWFINGEELDQDLINKIKDPDNKIFLSIASLWEIAIKHSLGKLPLQSEFSELKEILRNTNIEILPIEFSH
LQALLALPDIHNDPFDRIIIAQAIHEKLKLITRDSKFKNYPADITWV

Download         Length: 384 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7897.05 Da        Isoelectric Point: 4.3322

>AT269993 WP_273630153.1 NZ_CP117167:c5728289-5728086 [Mucilaginibacter jinjuensis]
MSDLDLYNSIIALPENLKEEVSDFVEFLKQKAEKKAEKKERVYGYAKGFFIIPPDFDEPLDVFKDYM

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References