Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 247877..248448 Replicon chromosome
Accession NZ_CP117159
Organism Sphingobium sp. AntQ-1

Toxin (Protein)


Gene name relE Uniprot ID A0A8G1ZF93
Locus tag sphantq_RS19990 Protein ID WP_066609131.1
Coordinates 248161..248448 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A8G1ZG49
Locus tag sphantq_RS19985 Protein ID WP_066609130.1
Coordinates 247877..248164 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
sphantq_RS19970 (sphantq_03961) 243802..245265 - 1464 WP_272800503.1 NAD-dependent succinate-semialdehyde dehydrogenase -
sphantq_RS19975 (sphantq_03962) 245262..246134 - 873 WP_272800504.1 GNAT family N-acetyltransferase -
sphantq_RS19980 (sphantq_03963) 246339..247811 + 1473 WP_272800505.1 aldehyde dehydrogenase family protein -
sphantq_RS19985 (sphantq_03964) 247877..248164 + 288 WP_066609130.1 hypothetical protein Antitoxin
sphantq_RS19990 (sphantq_03965) 248161..248448 + 288 WP_066609131.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
sphantq_RS19995 (sphantq_03966) 248458..249591 - 1134 WP_272800506.1 FAD-binding oxidoreductase -
sphantq_RS20000 (sphantq_03967) 249588..250961 - 1374 WP_272800507.1 NAD(P)/FAD-dependent oxidoreductase -
sphantq_RS20005 (sphantq_03968) 250943..251248 - 306 WP_129927148.1 (2Fe-2S)-binding protein -
sphantq_RS20010 (sphantq_03969) 251245..252168 - 924 WP_272800508.1 ATP-binding cassette domain-containing protein -
sphantq_RS20015 252572..253063 - 492 Protein_231 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11124.81 Da        Isoelectric Point: 11.3576

>T269984 WP_066609131.1 NZ_CP117159:248161-248448 [Sphingobium sp. AntQ-1]
MRLRWTADAVRDRDAIYDYVEARSPRAAIRLDTLFSQRAADLSRLPAMGRPGRVPGTRELIAHRNYILVYDLTDTDVRIL
RLLHAARLWPPQERR

Download         Length: 288 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10716.86 Da        Isoelectric Point: 7.3228

>AT269984 WP_066609130.1 NZ_CP117159:247877-248164 [Sphingobium sp. AntQ-1]
MNEATFTFRVDQELKGRFARAAKAQDRTGAQLLRDFMRDVVLREEQAESHDAWFRRQVDAGRASAQAGHLIAGDEVEAHF
AARRAATLRTSDGER

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References