Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 808957..809504 | Replicon | chromosome |
| Accession | NZ_CP117054 | ||
| Organism | Vibrio harveyi strain VH21FL | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | PQE20_RS03890 | Protein ID | WP_272759633.1 |
| Coordinates | 808957..809259 (-) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A7Y3ZEQ4 |
| Locus tag | PQE20_RS03895 | Protein ID | WP_015296907.1 |
| Coordinates | 809247..809504 (-) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PQE20_RS03840 (PQE20_03840) | 804397..804903 | - | 507 | WP_272759641.1 | YfbU family protein | - |
| PQE20_RS03845 (PQE20_03845) | 805030..805680 | - | 651 | WP_272759642.1 | phosphatidylinositol kinase | - |
| PQE20_RS03850 (PQE20_03850) | 805711..805804 | - | 94 | Protein_767 | DUF3265 domain-containing protein | - |
| PQE20_RS03855 (PQE20_03855) | 805910..806149 | - | 240 | WP_272759643.1 | hypothetical protein | - |
| PQE20_RS03860 (PQE20_03860) | 806314..806781 | - | 468 | WP_230544375.1 | DUF4476 domain-containing protein | - |
| PQE20_RS03865 (PQE20_03865) | 806822..806914 | - | 93 | WP_079879201.1 | DUF3265 domain-containing protein | - |
| PQE20_RS03870 (PQE20_03870) | 806935..807552 | - | 618 | WP_221069407.1 | LysE family translocator | - |
| PQE20_RS03875 (PQE20_03875) | 807710..808051 | - | 342 | WP_017191348.1 | hypothetical protein | - |
| PQE20_RS03880 (PQE20_03880) | 808191..808793 | - | 603 | WP_272759644.1 | class I SAM-dependent methyltransferase | - |
| PQE20_RS03885 (PQE20_03885) | 808829..808921 | - | 93 | WP_079858050.1 | DUF3265 domain-containing protein | - |
| PQE20_RS03890 (PQE20_03890) | 808957..809259 | - | 303 | WP_272759633.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| PQE20_RS03895 (PQE20_03895) | 809247..809504 | - | 258 | WP_015296907.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| PQE20_RS03900 (PQE20_03900) | 809586..809678 | - | 93 | WP_194842412.1 | DUF3265 domain-containing protein | - |
| PQE20_RS03905 (PQE20_03905) | 809693..810715 | - | 1023 | WP_141654583.1 | hypothetical protein | - |
| PQE20_RS03910 (PQE20_03910) | 810790..810882 | - | 93 | WP_005433818.1 | DUF3265 domain-containing protein | - |
| PQE20_RS03915 (PQE20_03915) | 810993..811820 | + | 828 | WP_272759645.1 | hypothetical protein | - |
| PQE20_RS03920 (PQE20_03920) | 811960..812514 | - | 555 | WP_023667333.1 | hypothetical protein | - |
| PQE20_RS03925 (PQE20_03925) | 813253..813777 | - | 525 | WP_272759646.1 | hypothetical protein | - |
| PQE20_RS03930 (PQE20_03930) | 814112..814399 | + | 288 | WP_272759647.1 | 2TM domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 739704..835952 | 96248 | |
| - | inside | Integron | - | - | 744386..835952 | 91566 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11653.57 Da Isoelectric Point: 5.8808
>T269980 WP_272759633.1 NZ_CP117054:c809259-808957 [Vibrio harveyi]
MAEVIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLRTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLGKQ
MAEVIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLRTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLGKQ
Download Length: 303 bp
>T269980 NZ_CP117054:c809259-808957 [Vibrio harveyi]
ATGGCTGAAGTAATCTGGACTGAACCAGCGTTATCTGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTACAAACGATCTTCTCCAAAGTCGAACGCCTACGAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAGCATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCTTGTTGGGTAAGCAATAG
ATGGCTGAAGTAATCTGGACTGAACCAGCGTTATCTGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTACAAACGATCTTCTCCAAAGTCGAACGCCTACGAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAGCATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCTTGTTGGGTAAGCAATAG
Antitoxin
Download Length: 86 a.a. Molecular weight: 9638.16 Da Isoelectric Point: 6.7269
>AT269980 WP_015296907.1 NZ_CP117054:c809504-809247 [Vibrio harveyi]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKMVSHDEAKDKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKMVSHDEAKDKM
SKWLK
Download Length: 258 bp
>AT269980 NZ_CP117054:c809504-809247 [Vibrio harveyi]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCCGATCTCCACGATACCAAAGAGCCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCTTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAATGGTAAGCCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAGTAA
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCCGATCTCCACGATACCAAAGAGCCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCTTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAATGGTAAGCCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|