Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 793095..793642 Replicon chromosome
Accession NZ_CP117054
Organism Vibrio harveyi strain VH21FL

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PQE20_RS03725 Protein ID WP_272759633.1
Coordinates 793095..793397 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U3A269
Locus tag PQE20_RS03730 Protein ID WP_005448240.1
Coordinates 793385..793642 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQE20_RS03670 (PQE20_03670) 788274..789212 - 939 WP_272759859.1 hypothetical protein -
PQE20_RS03675 (PQE20_03675) 789176..789268 - 93 WP_101945361.1 DUF3265 domain-containing protein -
PQE20_RS03680 (PQE20_03680) 789283..790281 - 999 WP_258479436.1 hypothetical protein -
PQE20_RS03685 (PQE20_03685) 790374..790484 - 111 WP_072609782.1 DUF3265 domain-containing protein -
PQE20_RS03690 (PQE20_03690) 790503..790964 - 462 WP_050903769.1 GNAT family N-acetyltransferase -
PQE20_RS03695 (PQE20_03695) 791131..791706 - 576 WP_272759631.1 hypothetical protein -
PQE20_RS03700 (PQE20_03700) 791734..791823 - 90 WP_079884698.1 DUF3265 domain-containing protein -
PQE20_RS03705 (PQE20_03705) 791841..792281 - 441 WP_272759632.1 hypothetical protein -
PQE20_RS03710 (PQE20_03710) 792319..792411 - 93 WP_078532186.1 DUF3265 domain-containing protein -
PQE20_RS03715 (PQE20_03715) 792426..792938 - 513 WP_053306502.1 hypothetical protein -
PQE20_RS03720 (PQE20_03720) 792967..793059 - 93 WP_004748931.1 DUF3265 domain-containing protein -
PQE20_RS03725 (PQE20_03725) 793095..793397 - 303 WP_272759633.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PQE20_RS03730 (PQE20_03730) 793385..793642 - 258 WP_005448240.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PQE20_RS03735 (PQE20_03735) 793844..794197 - 354 WP_025625246.1 DUF6404 family protein -
PQE20_RS03740 (PQE20_03740) 794370..794843 - 474 WP_195877583.1 hypothetical protein -
PQE20_RS03745 (PQE20_03745) 794871..795002 - 132 WP_167425888.1 DUF3265 domain-containing protein -
PQE20_RS03750 (PQE20_03750) 795406..795499 - 94 Protein_747 DUF3265 domain-containing protein -
PQE20_RS03755 (PQE20_03755) 795489..796124 - 636 WP_272759634.1 hypothetical protein -
PQE20_RS03760 (PQE20_03760) 796232..796684 - 453 WP_147270108.1 hypothetical protein -
PQE20_RS03765 (PQE20_03765) 796721..796813 - 93 WP_272759635.1 DUF3265 domain-containing protein -
PQE20_RS03770 (PQE20_03770) 796853..797158 - 306 WP_114732536.1 hypothetical protein -
PQE20_RS03775 (PQE20_03775) 797327..798484 - 1158 WP_069687262.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 739704..835952 96248
- inside Integron - - 744386..835952 91566


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11653.57 Da        Isoelectric Point: 5.8808

>T269979 WP_272759633.1 NZ_CP117054:c793397-793095 [Vibrio harveyi]
MAEVIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLRTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLGKQ

Download         Length: 303 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9606.10 Da        Isoelectric Point: 6.7269

>AT269979 WP_005448240.1 NZ_CP117054:c793642-793385 [Vibrio harveyi]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A432DGX8

References