Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2135965..2136236 Replicon chromosome
Accession NZ_CP117049
Organism Escherichia coli strain MLI106K2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2136095..2136198 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2135965..2136236 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL423_RS11485 2132520..2133182 - 663 WP_000944256.1 exodeoxyribonuclease X -
NL423_RS11490 2133206..2133862 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NL423_RS11495 2133964..2134194 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NL423_RS11500 2134333..2134707 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NL423_RS11505 2134711..2135583 + 873 WP_042346164.1 copper homeostasis membrane protein CopD -
NL423_RS11510 2135596..2135937 + 342 WP_000976476.1 YebY family protein -
- 2135965..2136236 - 272 - - Antitoxin
- 2136095..2136198 + 104 - - Toxin
NL423_RS11515 2136333..2136989 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NL423_RS11520 2136990..2137181 - 192 WP_000457842.1 YebW family protein -
NL423_RS11525 2137286..2137522 - 237 WP_001295499.1 YebV family protein -
NL423_RS11530 2137640..2139079 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269927 NZ_CP117049:2136095-2136198 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269927 NZ_CP117049:c2136236-2135965 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References