Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 869990..870650 Replicon chromosome
Accession NZ_CP117033
Organism Salmonella enterica strain PIW95_S14_0299

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag PQP07_RS04235 Protein ID WP_000244756.1
Coordinates 870237..870650 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PQP07_RS04230 Protein ID WP_000351186.1
Coordinates 869990..870256 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP07_RS04210 (865918) 865918..867351 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
PQP07_RS04215 (867510) 867510..867821 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
PQP07_RS04220 (867985) 867985..868644 + 660 WP_000250289.1 hemolysin III family protein -
PQP07_RS04225 (868760) 868760..869740 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
PQP07_RS04230 (869990) 869990..870256 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PQP07_RS04235 (870237) 870237..870650 + 414 WP_000244756.1 protein YgfX Toxin
PQP07_RS04240 (870703) 870703..871224 - 522 WP_001055885.1 flavodoxin FldB -
PQP07_RS04245 (871337) 871337..872233 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PQP07_RS04250 (872257) 872257..872970 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PQP07_RS04255 (872976) 872976..874709 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T269882 WP_000244756.1 NZ_CP117033:870237-870650 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT269882 WP_000351186.1 NZ_CP117033:869990-870256 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References