Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 2144690..2145338 Replicon chromosome
Accession NZ_CP117029
Organism Vibrio tubiashii strain FP17

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag LYZ37_RS09730 Protein ID WP_272785357.1
Coordinates 2144690..2145112 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag LYZ37_RS09735 Protein ID WP_272785358.1
Coordinates 2145105..2145338 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LYZ37_RS09700 (LYZ37_09700) 2140288..2140644 - 357 WP_272785352.1 hypothetical protein -
LYZ37_RS09705 (LYZ37_09705) 2140731..2141081 - 351 WP_272785353.1 DUF3147 family protein -
LYZ37_RS09710 (LYZ37_09710) 2141134..2142210 - 1077 WP_272785354.1 nickel/cobalt efflux protein RcnA -
LYZ37_RS09715 (LYZ37_09715) 2142345..2142617 + 273 WP_069666778.1 Ni(II)/Co(II)-binding transcriptional repressor RcnR -
LYZ37_RS09720 (LYZ37_09720) 2142689..2143750 - 1062 WP_272785355.1 protease SohB -
LYZ37_RS09725 (LYZ37_09725) 2143840..2144583 + 744 WP_272785356.1 YciK family oxidoreductase -
LYZ37_RS09730 (LYZ37_09730) 2144690..2145112 - 423 WP_272785357.1 type II toxin-antitoxin system VapC family toxin Toxin
LYZ37_RS09735 (LYZ37_09735) 2145105..2145338 - 234 WP_272785358.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LYZ37_RS09740 (LYZ37_09740) 2145549..2146226 + 678 WP_239825416.1 translesion DNA synthesis-associated protein ImuA -
LYZ37_RS09745 (LYZ37_09745) 2146229..2147629 + 1401 WP_272785359.1 DNA polymerase Y family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-131)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15667.40 Da        Isoelectric Point: 9.5032

>T269878 WP_272785357.1 NZ_CP117029:c2145112-2144690 [Vibrio tubiashii]
MSKKINYMLDTCICSFIMREQPITVLKKLQAVVGKQHRIVISAITYQEMQYGLLGKKASQKHKVLVEAFLKRVDEILPWD
KAAVDATTEVKRDLMAKGTPIGSNDTAIAGHAIAAGCVLVTNNTREFQRVEGLKLEDWVH

Download         Length: 423 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9023.01 Da        Isoelectric Point: 4.2495

>AT269878 WP_272785358.1 NZ_CP117029:c2145338-2145105 [Vibrio tubiashii]
MRTVSIFKNGKNQAVRLPKDFEFDGVNELEIHKEGDVITLRPARPDWLSFGEQEKADDDFMVNREDVMTDEGRFDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References