Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 3050482..3051067 Replicon chromosome
Accession NZ_CP117025
Organism Sphingomonas hankookensis strain SZ.B2R2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PPZ50_RS14420 Protein ID WP_272815365.1
Coordinates 3050738..3051067 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PPZ50_RS14415 Protein ID WP_272815364.1
Coordinates 3050482..3050745 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPZ50_RS14400 (PPZ50_14380) 3045961..3047853 + 1893 WP_272815362.1 hypothetical protein -
PPZ50_RS14405 (PPZ50_14385) 3047892..3049403 + 1512 WP_272815363.1 IS21 family transposase -
PPZ50_RS14410 (PPZ50_14390) 3049390..3050118 + 729 WP_066691143.1 IS21-like element helper ATPase IstB -
PPZ50_RS14415 (PPZ50_14395) 3050482..3050745 + 264 WP_272815364.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PPZ50_RS14420 (PPZ50_14400) 3050738..3051067 + 330 WP_272815365.1 type II toxin-antitoxin system YafQ family toxin Toxin
PPZ50_RS14425 (PPZ50_14405) 3051073..3053109 - 2037 WP_272815366.1 hypothetical protein -
PPZ50_RS14430 (PPZ50_14410) 3053394..3053612 - 219 WP_272815367.1 hypothetical protein -
PPZ50_RS14435 (PPZ50_14415) 3053873..3054589 + 717 WP_272815368.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3034942..3094687 59745


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(15-107)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11974.61 Da        Isoelectric Point: 9.0928

>T269876 WP_272815365.1 NZ_CP117025:3050738-3051067 [Sphingomonas hankookensis]
MAKGAQTKRASHPRACDYTKAFSKDWARLSGSGRYDMNRLKAVMLLLIANDAPLGPEWKDHPLKGEWSSHRECHVGGDFL
LIYKTDDGAGKGGTIVFVRAGTHADLFGE

Download         Length: 330 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9261.68 Da        Isoelectric Point: 5.0197

>AT269876 WP_272815364.1 NZ_CP117025:3050482-3050745 [Sphingomonas hankookensis]
MASTMLHVRLDEDIKTKGNAALAAMGLSAADAVRLLYHRIVADQALPLELKVPNAATRQAMLEADAIIASRADRFENGEA
MIGTLDG

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References