Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 962877..963148 Replicon chromosome
Accession NZ_CP117020
Organism Escherichia coli strain MLI106K3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 962915..963018 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 962877..963148 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL424_RS05015 960034..961473 + 1440 WP_049068043.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NL424_RS05020 961591..961827 + 237 WP_001295499.1 YebV family protein -
NL424_RS05025 961932..962123 + 192 WP_001296140.1 YebW family protein -
NL424_RS05030 962124..962780 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 962877..963148 + 272 - - Antitoxin
- 962915..963018 - 104 - - Toxin
NL424_RS05035 963176..963517 - 342 WP_000976472.1 YebY family protein -
NL424_RS05040 963530..964402 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NL424_RS05045 964406..964780 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NL424_RS05050 964919..965149 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NL424_RS05055 965251..965907 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NL424_RS05060 965931..966593 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 954647..986933 32286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269856 NZ_CP117020:c963018-962915 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269856 NZ_CP117020:962877-963148 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References