Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 648976..649244 Replicon chromosome
Accession NZ_CP117016
Organism Escherichia coli strain MLI121

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 649014..649117 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 648976..649244 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL415_RS03865 646133..647572 + 1440 WP_024186572.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NL415_RS03870 647690..647926 + 237 WP_001295499.1 YebV family protein -
NL415_RS03875 648031..648222 + 192 WP_001296140.1 YebW family protein -
NL415_RS03880 648223..648879 - 657 WP_001559255.1 protein-serine/threonine phosphatase -
- 648976..649244 + 269 - - Antitoxin
- 649014..649117 - 104 - - Toxin
NL415_RS03885 649274..649615 - 342 WP_000976485.1 YebY family protein -
NL415_RS03890 649628..650500 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
NL415_RS03895 650504..650878 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NL415_RS03900 651017..651247 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NL415_RS03905 651349..652005 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
NL415_RS03910 652029..652691 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269829 NZ_CP117016:c649117-649014 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT269829 NZ_CP117016:648976-649244 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References