Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2304471..2304739 Replicon chromosome
Accession NZ_CP117013
Organism Escherichia coli strain MLI114

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2304598..2304701 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2304471..2304739 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL414_RS11705 2301024..2301686 - 663 WP_000944256.1 exodeoxyribonuclease X -
NL414_RS11710 2301710..2302366 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
NL414_RS11715 2302468..2302698 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NL414_RS11720 2302837..2303211 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NL414_RS11725 2303215..2304087 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
NL414_RS11730 2304100..2304441 + 342 WP_000976485.1 YebY family protein -
- 2304471..2304739 - 269 - - Antitoxin
- 2304598..2304701 + 104 - - Toxin
NL414_RS11735 2304836..2305492 + 657 WP_001559255.1 protein-serine/threonine phosphatase -
NL414_RS11740 2305493..2305684 - 192 WP_001296140.1 YebW family protein -
NL414_RS11745 2305789..2306025 - 237 WP_001295499.1 YebV family protein -
NL414_RS11750 2306143..2307582 - 1440 WP_024186572.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2297159..2320568 23409


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269813 NZ_CP117013:2304598-2304701 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT269813 NZ_CP117013:c2304739-2304471 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References