Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2635173..2635444 Replicon chromosome
Accession NZ_CP117010
Organism Escherichia coli strain MLI110

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2635211..2635314 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2635173..2635444 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL413_RS13455 2632330..2633769 + 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NL413_RS13460 2633887..2634123 + 237 WP_001338166.1 YebV family protein -
NL413_RS13465 2634228..2634419 + 192 WP_001338167.1 YebW family protein -
NL413_RS13470 2634420..2635076 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 2635173..2635444 + 272 - - Antitoxin
- 2635211..2635314 - 104 - - Toxin
NL413_RS13475 2635472..2635813 - 342 WP_000976472.1 YebY family protein -
NL413_RS13480 2635826..2636698 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
NL413_RS13485 2636702..2637076 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NL413_RS13490 2637215..2637445 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NL413_RS13495 2637547..2638203 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NL413_RS13500 2638227..2638889 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269796 NZ_CP117010:c2635314-2635211 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269796 NZ_CP117010:2635173-2635444 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References