Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2902754..2903025 Replicon chromosome
Accession NZ_CP117008
Organism Escherichia coli strain MLI109

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2902792..2902895 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2902754..2903025 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL412_RS15015 2899911..2901350 + 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NL412_RS15020 2901468..2901704 + 237 WP_001295499.1 YebV family protein -
NL412_RS15025 2901809..2902000 + 192 WP_001296140.1 YebW family protein -
NL412_RS15030 2902001..2902657 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 2902754..2903025 + 272 - - Antitoxin
- 2902792..2902895 - 104 - - Toxin
NL412_RS15035 2903053..2903394 - 342 WP_000976472.1 YebY family protein -
NL412_RS15040 2903407..2904279 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NL412_RS15045 2904283..2904657 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NL412_RS15050 2904796..2905026 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NL412_RS15055 2905128..2905784 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NL412_RS15060 2905808..2906470 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - galU / kdsA 2886914..3035241 148327


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269774 NZ_CP117008:c2902895-2902792 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269774 NZ_CP117008:2902754-2903025 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References