Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 3757908..3758484 | Replicon | chromosome |
Accession | NZ_CP117001 | ||
Organism | Escherichia coli strain MLI108K2 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | D3GXZ2 |
Locus tag | NL410_RS20240 | Protein ID | WP_001297643.1 |
Coordinates | 3757908..3758195 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A829G8Z0 |
Locus tag | NL410_RS20245 | Protein ID | WP_000063156.1 |
Coordinates | 3758182..3758484 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NL410_RS20220 (3754161) | 3754161..3755441 | - | 1281 | WP_001037380.1 | DUF445 domain-containing protein | - |
NL410_RS20225 (3755482) | 3755482..3756714 | - | 1233 | WP_001380906.1 | multidrug efflux MFS transporter MdtM | - |
NL410_RS20230 (3756860) | 3756860..3756955 | - | 96 | Protein_3603 | dienelactone hydrolase family protein | - |
NL410_RS20235 (3757012) | 3757012..3757709 | + | 698 | Protein_3604 | IS1 family transposase | - |
NL410_RS20240 (3757908) | 3757908..3758195 | + | 288 | WP_001297643.1 | BrnT family toxin | Toxin |
NL410_RS20245 (3758182) | 3758182..3758484 | + | 303 | WP_000063156.1 | BrnA antitoxin family protein | Antitoxin |
NL410_RS20250 (3758518) | 3758518..3759474 | - | 957 | WP_001297640.1 | GTPase | - |
NL410_RS20255 (3759485) | 3759485..3759688 | - | 204 | WP_000467859.1 | YbdD/YjiX family protein | - |
NL410_RS20260 (3759738) | 3759738..3761888 | - | 2151 | WP_001295524.1 | pyruvate/proton symporter BtsT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829GEV9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829G8Z0 |