Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1047128..1047399 Replicon chromosome
Accession NZ_CP116994
Organism Escherichia coli strain MLI108K1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1047166..1047269 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1047128..1047399 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL409_RS07055 1044285..1045724 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NL409_RS07060 1045842..1046078 + 237 WP_001295499.1 YebV family protein -
NL409_RS07065 1046183..1046374 + 192 WP_000457842.1 YebW family protein -
NL409_RS07070 1046375..1047031 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1047128..1047399 + 272 - - Antitoxin
- 1047166..1047269 - 104 - - Toxin
NL409_RS07075 1047427..1047768 - 342 WP_000976476.1 YebY family protein -
NL409_RS07080 1047781..1048653 - 873 WP_046464082.1 copper homeostasis membrane protein CopD -
NL409_RS07085 1048657..1049031 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NL409_RS07090 1049170..1049400 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NL409_RS07095 1049502..1050158 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NL409_RS07100 1050182..1050844 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269680 NZ_CP116994:c1047269-1047166 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269680 NZ_CP116994:1047128-1047399 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References