Detailed information of TA system TA026954

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-MqsA
• Location: 1866162..1866897
• Replicon: chromosome
• Accession: NC_017531
• Organism: Pantoea ananatis AJ13355

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PAJ_RS08590
• Protein ID: WP_041930820.1
• Coordinates: 1866505..1866897 (-)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PAJ_RS08585
• Protein ID: WP_041930819.1
• Coordinates: 1866162..1866515 (-)
• Length: 118 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PAJ_RS08555	1862791..1863477	+	687	WP_014593911.1	two-component system response regulator PmrA	-
PAJ_RS08560	1863474..1864541	+	1068	WP_013026114.1	two-component system sensor histidine kinase PmrB	-
PAJ_RS08565	1864904..1865443	+	540	WP_013026115.1	peptide-methionine (S)-S-oxide reductase MsrA	-
PAJ_RS08585	1866162..1866515	-	354	WP_041930819.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
PAJ_RS08590	1866505..1866897	-	393	WP_041930820.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PAJ_RS08595	1867222..1868169	-	948	WP_014593912.1	sulfonate ABC transporter substrate-binding protein	-
PAJ_RS08600	1868264..1870150	-	1887	WP_041931008.1	aliphatic sulfonate ABC transporter substrate-binding protein	-
PAJ_RS08605	1870429..1871601	+	1173	WP_013026120.1	FMNH2-dependent alkanesulfonate monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (6-125)

Antitoxin

• Cro/C1-type helix-turn-helix domain (56-99)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14987.31 Da
• Isoelectric Point: 10.1482

>T26954 WP_041930820.1 NC_017531:c1866897-1866505 [Pantoea ananatis AJ13355]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVFTGVFEADLGGGVIKKRLALHQGKRGGARTVIFFRQGTNLVYYDGWVK
NLSRKYAKEIDEDQLDTYRDVARMFFRVNSEVMSLLVRSGMVREVKCNEN

Nucleotide

• Length: 393 bp

>T26954 NC_017531:c1866897-1866505 [Pantoea ananatis AJ13355]
ATGGGTTTTACGCTTTATGTTCATAAACGTTTTGACAGAGTGTTTAAAAAAACGCGTCTGACAGACAGCGTCCTGTGTTA
CGCAGCAGGTGACGTTTTTACTGGCGTGTTTGAGGCTGACTTAGGCGGTGGCGTTATTAAAAAGCGTCTTGCTCTTCACC
AAGGCAAGCGTGGCGGCGCGCGAACGGTCATCTTCTTCAGACAAGGCACCAACCTGGTTTATTACGATGGATGGGTTAAA
AACTTGTCGAGGAAATACGCTAAAGAAATCGATGAAGATCAGCTGGATACCTACAGGGATGTGGCAAGAATGTTTTTCCG
TGTAAATAGTGAAGTGATGAGCCTGCTCGTCAGAAGCGGAATGGTCAGAGAGGTTAAATGTAATGAAAACTGA

Antitoxin

Protein

• Length: 118 a.a.
• Molecular weight: 13095.20 Da
• Isoelectric Point: 9.8885

>AT26954 WP_041930819.1 NC_017531:c1866515-1866162 [Pantoea ananatis AJ13355]
MKTEPAELSELLEDAKAFHALGLATDKEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Nucleotide

• Length: 354 bp

>AT26954 NC_017531:c1866515-1866162 [Pantoea ananatis AJ13355]
ATGAAAACTGAACCCGCCGAATTGAGTGAACTACTTGAAGATGCGAAAGCGTTTCACGCGTTAGGACTGGCAACAGATAA
AGAAGTGGAGTCCATAGCAAAGCGCGCAAAAAATCGTGAACTCCGTGCCCGTATTGCATCAGTAAAGCCCATGACAGCAA
CTGAAATCAAAGACGTGCGCATGCGTTGGGGAATGTCGCAATCGCTTGTGGCGCTCTCATTTGGCATGACGGTCGATAGC
GTATCGAAATGGGAGCGAGGTGAAATCACACCGAGCCCACCGGTGATGCGGATGCTACAACTCCTTCGCGATAACGGCCC
TGAACTCTTTACCTCTAAGCATCAAGGTATCTAG