Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 19454..20010 Replicon plasmid p2939_90_3
Accession NZ_CP116946
Organism Providencia alcalifaciens strain 2939/90

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PO864_RS20535 Protein ID WP_282490785.1
Coordinates 19454..19729 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PO864_RS20540 Protein ID WP_282490786.1
Coordinates 19720..20010 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO864_RS20525 (PO864_20760) 14749..17640 - 2892 WP_282490782.1 conjugal transfer mating-pair stabilization protein TraG -
PO864_RS20530 (PO864_20765) 17653..19029 - 1377 WP_282490783.1 conjugal transfer pilus assembly protein TraH -
PO864_RS20535 (PO864_20770) 19454..19729 - 276 WP_282490785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO864_RS20540 (PO864_20775) 19720..20010 - 291 WP_282490786.1 ribbon-helix-helix domain-containing protein Antitoxin
PO864_RS20545 (PO864_20780) 20069..20599 - 531 WP_282490788.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
PO864_RS20550 (PO864_20785) 20605..20895 - 291 WP_282490789.1 hypothetical protein -
PO864_RS20555 (PO864_20790) 20916..21671 - 756 WP_282490794.1 type-F conjugative transfer system pilin assembly protein TraF -
PO864_RS20560 21857..22846 - 990 Protein_17 conjugal transfer protein TraN -
PO864_RS20565 (PO864_20800) 23512..24147 - 636 WP_282490790.1 type-F conjugative transfer system pilin assembly protein TrbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..58284 58284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-52)

Antitoxin

Ribbon-helix-helix protein, CopG

(13-50)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10020.76 Da        Isoelectric Point: 9.4165

>T269520 WP_282490785.1 NZ_CP116946:c19729-19454 [Providencia alcalifaciens]
MELKWTSKALSDLSRVYDFLALSNSVAAARVVQTLTKAPMLLLIKNPRMGEQLFQFIARDLADMGISGRRFALNIDVTPA
TAGNSNCCCIR

Download         Length: 276 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10817.28 Da        Isoelectric Point: 4.7962

>AT269520 WP_282490786.1 NZ_CP116946:c20010-19720 [Providencia alcalifaciens]
MKNSSVQNKTKVLTAHVPLTMADKIDEIAERLERSRGWVMKQALSTWIAQEEMRDTLTREALLDVESGQVIDNQSVQDWA
ASLNTDLPLPVPRWN

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References