Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1436283..1437202 Replicon chromosome
Accession NZ_CP116941
Organism Bacillus licheniformis strain GN02

Toxin (Protein)


Gene name spoIISA Uniprot ID T5HIF3
Locus tag OSR41_RS07390 Protein ID WP_003180879.1
Coordinates 1436456..1437202 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID T5HT37
Locus tag OSR41_RS07385 Protein ID WP_003180877.1
Coordinates 1436283..1436456 (-) Length 58 a.a.

Genomic Context


OSR41_RS07360OSR41_RS07365OSR41_RS07370OSR41_RS07375OSR41_RS07405OSR41_RS07410OSR41_RS07380OSR41_RS07385OSR41_RS07390OSR41_RS07395OSR41_RS07400
Location: 1431708..1432805 (1098 bp)
Type: Others
Protein ID: WP_003180867.1
Location: 1432781..1433629 (849 bp)
Type: Others
Protein ID: WP_009328728.1
Location: 1433656..1434669 (1014 bp)
Type: Others
Protein ID: WP_003180872.1
Location: 1434722..1435993 (1272 bp)
Type: Others
Protein ID: WP_011197811.1
Location: 1439273..1441030 (1758 bp)
Type: Others
Protein ID: WP_003180886.1
Location: 1441159..1441803 (645 bp)
Type: Others
Protein ID: WP_009328721.1
Location: 1436056..1436187 (132 bp)
Type: Others
Protein ID: WP_003180875.1
Location: 1436283..1436456 (174 bp)
Type: Antitoxin
Protein ID: WP_003180877.1
Location: 1436456..1437202 (747 bp)
Type: Toxin
Protein ID: WP_003180879.1
Location: 1437313..1438311 (999 bp)
Type: Others
Protein ID: WP_009328723.1
Location: 1438324..1438941 (618 bp)
Type: Others
Protein ID: WP_003180884.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OSR41_RS07360 (OSR41_07360)1431708..1432805+1098WP_003180867.1mannonate dehydratase-
OSR41_RS07365 (OSR41_07365)1432781..1433629+849WP_009328728.1SDR family oxidoreductase-
OSR41_RS07370 (OSR41_07370)1433656..1434669+1014WP_003180872.1zinc-binding alcohol dehydrogenase family protein-
OSR41_RS07375 (OSR41_07375)1434722..1435993+1272WP_011197811.1MFS transporter-
OSR41_RS07380 (OSR41_07380)1436056..1436187-132WP_003180875.1hypothetical protein-
OSR41_RS07385 (OSR41_07385)1436283..1436456-174WP_003180877.1type II toxin-antitoxin system SpoIISB family antitoxinAntitoxin
OSR41_RS07390 (OSR41_07390)1436456..1437202-747WP_003180879.1type II toxin-antitoxin system SpoIISA family toxinToxin
OSR41_RS07395 (OSR41_07395)1437313..1438311-999WP_009328723.1inorganic phosphate transporter-
OSR41_RS07400 (OSR41_07400)1438324..1438941-618WP_003180884.1DUF47 domain-containing protein-
OSR41_RS07405 (OSR41_07405)1439273..1441030+1758WP_003180886.1gamma-glutamyltransferase-
OSR41_RS07410 (OSR41_07410)1441159..1441803+645WP_009328721.1YesL family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-238)

Antitoxin

(1-57)


Sequences


Toxin        


Download         Length: 249 a.a.        Molecular weight: 29391.80 Da        Isoelectric Point: 4.5367

>T269516 WP_003180879.1 NZ_CP116941:c1437202-1436456 [Bacillus licheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKQLAEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLDRKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD

Download         Length: 747 bp


Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6945.04 Da        Isoelectric Point: 10.9186

>AT269516 WP_003180877.1 NZ_CP116941:c1436456-1436283 [Bacillus licheniformis]
MEPAFQQDQESVKKRLAFKMFKRQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBT5HIF3


Antitoxin

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Source
ID
Structure
AlphaFold DBT5HT37

References