Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2082530..2082801 Replicon chromosome
Accession NZ_CP116931
Organism Escherichia coli strain MLI106K1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2082660..2082763 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2082530..2082801 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL422_RS10630 2079085..2079747 - 663 WP_000944256.1 exodeoxyribonuclease X -
NL422_RS10635 2079771..2080427 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NL422_RS10640 2080529..2080759 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NL422_RS10645 2080898..2081272 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NL422_RS10650 2081276..2082148 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NL422_RS10655 2082161..2082502 + 342 WP_000976472.1 YebY family protein -
- 2082530..2082801 - 272 - - Antitoxin
- 2082660..2082763 + 104 - - Toxin
NL422_RS10660 2082898..2083554 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
NL422_RS10665 2083555..2083746 - 192 WP_001296140.1 YebW family protein -
NL422_RS10670 2083851..2084087 - 237 WP_001295499.1 YebV family protein -
NL422_RS10675 2084205..2085644 - 1440 WP_049068043.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2075220..2085650 10430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269499 NZ_CP116931:2082660-2082763 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269499 NZ_CP116931:c2082801-2082530 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References