Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1900359..1900630 Replicon chromosome
Accession NZ_CP116929
Organism Escherichia coli strain MLI105

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1900489..1900592 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1900359..1900630 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL421_RS09360 1896914..1897576 - 663 WP_000944256.1 exodeoxyribonuclease X -
NL421_RS09365 1897600..1898256 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NL421_RS09370 1898358..1898588 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NL421_RS09375 1898727..1899101 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NL421_RS09380 1899105..1899977 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
NL421_RS09385 1899990..1900331 + 342 WP_000976476.1 YebY family protein -
- 1900359..1900630 - 272 - - Antitoxin
- 1900489..1900592 + 104 - - Toxin
NL421_RS09390 1900727..1901383 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NL421_RS09395 1901384..1901575 - 192 WP_000457842.1 YebW family protein -
NL421_RS09400 1901680..1901916 - 237 WP_001295499.1 YebV family protein -
NL421_RS09405 1902034..1903473 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269479 NZ_CP116929:1900489-1900592 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269479 NZ_CP116929:c1900630-1900359 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References