Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2091016..2091287 Replicon chromosome
Accession NZ_CP116925
Organism Escherichia coli strain MLI104K2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2091146..2091249 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2091016..2091287 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL420_RS10905 2087571..2088233 - 663 WP_000944258.1 exodeoxyribonuclease X -
NL420_RS10910 2088257..2088913 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NL420_RS10915 2089015..2089245 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NL420_RS10920 2089384..2089758 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NL420_RS10925 2089762..2090634 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
NL420_RS10930 2090647..2090988 + 342 WP_072667349.1 YebY family protein -
- 2091016..2091287 - 272 - - Antitoxin
- 2091146..2091249 + 104 - - Toxin
NL420_RS10935 2091384..2092040 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
NL420_RS10940 2092041..2092232 - 192 WP_001338167.1 YebW family protein -
NL420_RS10945 2092337..2092573 - 237 WP_072667348.1 DUF1480 family protein -
NL420_RS10950 2092691..2094130 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269460 NZ_CP116925:2091146-2091249 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269460 NZ_CP116925:c2091287-2091016 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References