26944

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 409513..410130 Replicon chromosome
Accession NC_017531
Organism Pantoea ananatis AJ13355

Toxin (Protein)


Gene name Hha Uniprot ID D4GLR0
Locus tag PAJ_RS01805 Protein ID WP_013024903.1
Coordinates 409513..409728 (-) Length 72 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A8A4KA49
Locus tag PAJ_RS01810 Protein ID WP_015700827.1
Coordinates 409753..410130 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAJ_RS01775 405434..405772 + 339 WP_013024898.1 P-II family nitrogen regulator -
PAJ_RS01780 405806..407095 + 1290 WP_014606435.1 ammonium transporter AmtB -
PAJ_RS01785 407142..408005 - 864 WP_014593086.1 acyl-CoA thioesterase II -
PAJ_RS01790 408198..408755 + 558 WP_013024901.1 YbaY family lipoprotein -
PAJ_RS01795 408804..409115 - 312 WP_015700828.1 MGMT family protein -
PAJ_RS01805 409513..409728 - 216 WP_013024903.1 hemolysin expression modulator Hha Toxin
PAJ_RS01810 409753..410130 - 378 WP_015700827.1 Hha toxicity modulator TomB Antitoxin
PAJ_RS01815 410277..410630 - 354 WP_013024905.1 hypothetical protein -
PAJ_RS01820 410984..411652 + 669 WP_014606429.1 ABC transporter ATP-binding protein -
PAJ_RS01825 411649..412488 + 840 WP_013024907.1 metal ABC transporter permease -
PAJ_RS01830 412501..413379 + 879 WP_014593089.1 metal ABC transporter substrate-binding protein -
PAJ_RS01835 413439..413579 - 141 WP_014606428.1 type B 50S ribosomal protein L36 -
PAJ_RS01840 413591..413845 - 255 WP_014606427.1 type B 50S ribosomal protein L31 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(12-68)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8552.98 Da        Isoelectric Point: 9.4825

>T26944 WP_013024903.1 NC_017531:c409728-409513 [Pantoea ananatis AJ13355]
MNKTLTKTDYLMRLRRCRSIDTLERVIEKNKYELPDEELAVFYSAADHRLAELTMNKLYDKVPVSVWKFVR

Download         Length: 216 bp

>T26944 NC_017531:c409728-409513 [Pantoea ananatis AJ13355]
ATGAACAAAACCCTAACTAAAACTGATTATTTGATGCGACTGAGGCGCTGTCGTTCTATTGACACGCTGGAACGCGTGAT
TGAAAAAAATAAGTACGAATTACCCGATGAAGAATTAGCAGTATTTTACTCAGCAGCCGATCACCGCCTGGCTGAACTGA
CGATGAACAAGCTCTATGACAAAGTCCCGGTGTCAGTCTGGAAATTTGTACGCTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14722.35 Da        Isoelectric Point: 4.3976

>AT26944 WP_015700827.1 NC_017531:c410130-409753 [Pantoea ananatis AJ13355]
MDEYSPKRHDIAQLKYLCENLFDDSMATLTDSHHGWVNDPTAESNLQLNDLIEHIASFTMNYKIKHVEDEALITQIDEYL
DDTFMLFSNYSVNTQDLQRWQRSAKRLFNVFTEECAFLQQPSHSL

Download         Length: 378 bp

>AT26944 NC_017531:c410130-409753 [Pantoea ananatis AJ13355]
ATGGACGAATACTCACCGAAACGGCATGATATTGCCCAGCTTAAATACTTGTGTGAGAATCTGTTTGACGACAGCATGGC
GACATTAACTGACAGTCATCACGGCTGGGTTAATGACCCCACTGCCGAAAGCAATTTACAGCTAAACGATTTGATTGAGC
ACATCGCCTCTTTCACCATGAATTACAAAATTAAGCACGTTGAAGACGAAGCACTGATTACCCAAATCGATGAATATCTT
GATGATACCTTTATGCTGTTTAGCAACTACAGTGTAAATACTCAGGATCTTCAGCGCTGGCAACGCTCAGCGAAACGTTT
ATTTAATGTGTTTACTGAAGAGTGCGCTTTTCTTCAACAGCCAAGCCATTCATTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References