269336

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-mazE/MazF-ParD
Location 3456611..3457249 Replicon chromosome
Accession NZ_CP116902
Organism Aneurinibacillus sp. B1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PO771_RS17225 Protein ID WP_096467534.1
Coordinates 3456611..3456961 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PO771_RS17230 Protein ID WP_272560880.1
Coordinates 3456965..3457249 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO771_RS17195 (PO771_17195) 3451722..3452201 - 480 WP_272560874.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
PO771_RS17200 (PO771_17200) 3452233..3453249 - 1017 WP_272560875.1 thiamine-phosphate kinase -
PO771_RS17205 (PO771_17205) 3453246..3453719 - 474 WP_272560876.1 SprT family protein -
PO771_RS17210 (PO771_17210) 3453814..3454158 + 345 WP_272560877.1 hydrolase/acyltransferase -
PO771_RS17215 (PO771_17215) 3454232..3454351 + 120 WP_272560878.1 cortex morphogenetic protein CmpA -
PO771_RS17220 (PO771_17220) 3454375..3456528 - 2154 WP_272560879.1 Tex family protein -
PO771_RS17225 (PO771_17225) 3456611..3456961 - 351 WP_096467534.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PO771_RS17230 (PO771_17230) 3456965..3457249 - 285 WP_272560880.1 ribbon-helix-helix protein, CopG family Antitoxin
PO771_RS17235 (PO771_17235) 3457520..3458707 - 1188 WP_272560881.1 alanine racemase -
PO771_RS17240 (PO771_17240) 3458864..3459409 + 546 WP_272560882.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12917.86 Da        Isoelectric Point: 4.8435

>T269336 WP_096467534.1 NZ_CP116902:c3456961-3456611 [Aneurinibacillus sp. B1]
VIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKSYAFDRDSVILLEQI
RTIDKQRLTDKITHLDEEMMDRVNDALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11052.92 Da        Isoelectric Point: 7.3198

>AT269336 WP_272560880.1 NZ_CP116902:c3457249-3456965 [Aneurinibacillus sp. B1]
MVLSKMDTKRIMISLPDHLLQEVDGLVEKEKSNRSEFIRQAMRLYLKERKKRHIREMMQRGYMEMANINLHMASEAFEAE
EEADLTLGRLVSGV

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References