Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-mazE/MazF-ParD
Location 567283..567915 Replicon chromosome
Accession NZ_CP116887
Organism Aneurinibacillus sp. Ricciae_BoGa-3

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PP175_RS03065 Protein ID WP_027416684.1
Coordinates 567565..567915 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PP175_RS03060 Protein ID WP_272441386.1
Coordinates 567283..567561 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PP175_RS03030 (PP175_03030) 564069..564683 - 615 WP_272441383.1 hypothetical protein -
PP175_RS03050 (PP175_03050) 565385..565825 + 441 WP_272441384.1 hypothetical protein -
PP175_RS03055 (PP175_03055) 565831..567003 + 1173 WP_272441385.1 alanine racemase -
PP175_RS03060 (PP175_03060) 567283..567561 + 279 WP_272441386.1 CopG family ribbon-helix-helix protein Antitoxin
PP175_RS03065 (PP175_03065) 567565..567915 + 351 WP_027416684.1 type II toxin-antitoxin system endoribonuclease NdoA Toxin
PP175_RS03070 (PP175_03070) 568113..570272 + 2160 WP_272441387.1 Tex family protein -
PP175_RS03075 (PP175_03075) 570297..570419 - 123 WP_272441388.1 cortex morphogenetic protein CmpA -
PP175_RS03080 (PP175_03080) 570509..570988 + 480 WP_272441389.1 SprT family protein -
PP175_RS03085 (PP175_03085) 570972..572036 + 1065 WP_272441390.1 thiamine-phosphate kinase -
PP175_RS03090 (PP175_03090) 572041..572520 + 480 WP_272441391.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12929.92 Da        Isoelectric Point: 4.8668

>T269303 WP_027416684.1 NZ_CP116887:567565-567915 [Aneurinibacillus sp. Ricciae_BoGa-3]
VIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKAYAFDRDSVILLEQI
RTIDKQRLTDKITHLDEEMMERVNEALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10807.59 Da        Isoelectric Point: 7.8264

>AT269303 WP_272441386.1 NZ_CP116887:567283-567561 [Aneurinibacillus sp. Ricciae_BoGa-3]
MSKMDTKRIMISLPDHLLQEVDGLVEKEKSNRSEFIRQAMRLYLKERKKRQIRETMQRGYMEMANINLNLCCEAFQAEEE
ADLTLGRLVSGV

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References