Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4684625..4685277 Replicon chromosome
Accession NZ_CP116810
Organism Rhodopseudomonas palustris CGA009

Toxin (Protein)


Gene name vapC Uniprot ID Q6N2A8
Locus tag TX73_RS21470 Protein ID WP_011159677.1
Coordinates 4684873..4685277 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q6N2A9
Locus tag TX73_RS21465 Protein ID WP_011159676.1
Coordinates 4684625..4684876 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TX73_RS21455 (TX73_021455) 4679787..4680170 - 384 WP_011159673.1 phasin -
TX73_RS21460 (TX73_021460) 4680495..4684076 + 3582 WP_042441275.1 histidine kinase dimerization/phospho-acceptor domain-containing protein -
TX73_RS21465 (TX73_021465) 4684625..4684876 + 252 WP_011159676.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
TX73_RS21470 (TX73_021470) 4684873..4685277 + 405 WP_011159677.1 type II toxin-antitoxin system VapC family toxin Toxin
TX73_RS21475 (TX73_021475) 4685361..4686071 + 711 WP_011159678.1 Crp/Fnr family transcriptional regulator -
TX73_RS21480 (TX73_021480) 4686044..4686268 - 225 WP_011159679.1 DUF1858 domain-containing protein -
TX73_RS21485 (TX73_021485) 4686506..4687618 + 1113 WP_011159680.1 copper-containing nitrite reductase -
TX73_RS21490 (TX73_021490) 4687787..4688668 + 882 WP_011159681.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin

Antitoxin VapB-like

(1-82)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14406.53 Da        Isoelectric Point: 4.8780

>T269258 WP_011159677.1 NZ_CP116810:4684873-4685277 [Rhodopseudomonas palustris CGA009]
VIVIDTSAIIAIFREEPEAAQFARLIASDDQPVLSSGNLLETAIVLRGLKDIQPAKAERWLDDFIAEAGIRIEPVTTEQA
GYARSAHLRFGKGTGHKAALNYGDCFAYALAKALNAPLLCKGNDFPLTDIPLVA

Download         Length: 405 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9293.42 Da        Isoelectric Point: 6.7249

>AT269258 WP_011159676.1 NZ_CP116810:4684625-4684876 [Rhodopseudomonas palustris CGA009]
MHLNIKNDEAHQLATELARMTGESLTAAVTNALREQLAREHRRRQTDQIAQRLLKIGGRYAALPDTGRTPDEILGYDENG
LPT

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N2A8

Antitoxin

Source ID Structure
AlphaFold DB Q6N2A9

References