Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4675845..4676630 Replicon chromosome
Accession NZ_CP116810
Organism Rhodopseudomonas palustris CGA009

Toxin (Protein)


Gene name tacT Uniprot ID Q6N2B5
Locus tag TX73_RS21425 Protein ID WP_011159670.1
Coordinates 4675845..4676342 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag TX73_RS21430 Protein ID WP_042441274.1
Coordinates 4676343..4676630 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TX73_RS21395 (TX73_021395) 4670966..4671316 + 351 WP_011159664.1 helix-turn-helix transcriptional regulator -
TX73_RS21400 (TX73_021400) 4671313..4672206 + 894 WP_011159665.1 ImmA/IrrE family metallo-endopeptidase -
TX73_RS21405 (TX73_021405) 4672421..4672885 - 465 WP_011159666.1 CopG family transcriptional regulator -
TX73_RS21410 (TX73_021410) 4672895..4674889 - 1995 WP_011159667.1 conjugal transfer protein TraG -
TX73_RS21415 (TX73_021415) 4675023..4675322 - 300 WP_011159668.1 DUF2285 domain-containing protein -
TX73_RS21420 (TX73_021420) 4675430..4675708 + 279 WP_011159669.1 helix-turn-helix transcriptional regulator -
TX73_RS21425 (TX73_021425) 4675845..4676342 - 498 WP_011159670.1 GNAT family N-acetyltransferase Toxin
TX73_RS21430 (TX73_021430) 4676343..4676630 - 288 WP_042441274.1 DUF1778 domain-containing protein Antitoxin
TX73_RS21435 (TX73_021435) 4676701..4676931 - 231 Protein_4243 DUF3363 domain-containing protein -
TX73_RS21440 (TX73_021440) 4676962..4678527 + 1566 WP_065814273.1 DNA topoisomerase -
TX73_RS21450 (TX73_021450) 4679132..4679563 - 432 WP_011159672.1 phasin -
TX73_RS21455 (TX73_021455) 4679787..4680170 - 384 WP_011159673.1 phasin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(38-142)

Antitoxin

Vibrio phage ICP1, Orf50

(9-84)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18315.15 Da        Isoelectric Point: 8.8691

>T269257 WP_011159670.1 NZ_CP116810:c4676342-4675845 [Rhodopseudomonas palustris CGA009]
MTFRIEKLRREHHVEGFDCGKEPLNRFLLRYALQSQLSNSSQTYLALSQDEVVGFYTLAFGDVSYEDAPERLRKGVARHP
IPLMILARLAVASAWAGKGIGAGLLKDALARTLAAAEIAGLRAFAVHAKDDQARAFYERFDFIASPSDPMHLFVLLKDVR
ALIGP

Download         Length: 498 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10492.91 Da        Isoelectric Point: 5.1425

>AT269257 WP_042441274.1 NZ_CP116810:c4676630-4676343 [Rhodopseudomonas palustris CGA009]
MANAIRSEKLDLRLTPEAKRLLNAAAQASRRSVSEFVLESALDRAQEALPDRQHFGLDAAGWEAFLAALDAPARPLPRLQ
RLLTEPSVFEQAPTE

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N2B5

Antitoxin

Source ID Structure

References