Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3933423..3934078 Replicon chromosome
Accession NZ_CP116810
Organism Rhodopseudomonas palustris CGA009

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag TX73_RS18030 Protein ID WP_042441199.1
Coordinates 3933423..3933827 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag TX73_RS18035 Protein ID WP_042441643.1
Coordinates 3933824..3934078 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TX73_RS18015 (TX73_018015) 3928438..3928680 - 243 WP_011159021.1 hypothetical protein -
TX73_RS18020 (TX73_018020) 3929017..3930240 + 1224 WP_011159022.1 efflux RND transporter periplasmic adaptor subunit -
TX73_RS18025 (TX73_018025) 3930243..3933380 + 3138 WP_011159023.1 multidrug efflux RND transporter permease subunit -
TX73_RS18030 (TX73_018030) 3933423..3933827 - 405 WP_042441199.1 PIN domain-containing protein Toxin
TX73_RS18035 (TX73_018035) 3933824..3934078 - 255 WP_042441643.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
TX73_RS18045 (TX73_018045) 3934533..3934664 + 132 WP_267793647.1 hypothetical protein -
TX73_RS18050 (TX73_018050) 3934675..3935868 - 1194 WP_011159025.1 CoA transferase -
TX73_RS18055 (TX73_018055) 3935978..3937189 - 1212 WP_011159026.1 ABC transporter substrate-binding protein -
TX73_RS18060 (TX73_018060) 3937438..3938052 - 615 WP_011159027.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-115)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14748.64 Da        Isoelectric Point: 5.8886

>T269255 WP_042441199.1 NZ_CP116810:c3933827-3933423 [Rhodopseudomonas palustris CGA009]
VRAFFDTNILVYSTTSDPRQATAAACLEQGGFASVQVLNEFVHVARRKLRHDWPQIEVALEQFHAALDDVLPITLTTHAA
AVVLARDHRVSFYDALIVAAAQAAGCDVLYSEDLQHGRTFGALRVENPFLEGSR

Download         Length: 405 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9900.21 Da        Isoelectric Point: 4.9534

>AT269255 WP_042441643.1 NZ_CP116810:c3934078-3933824 [Rhodopseudomonas palustris CGA009]
MLVSKWGNSLAVRLPKALVDKLDLKEGDELNVVDIVERTLVVEKEDRRKAAVERLSRLRWTLPTDYKFDRDEANERYRDE
SNEP

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References