Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2243487..2244157 Replicon chromosome
Accession NZ_CP116810
Organism Rhodopseudomonas palustris CGA009

Toxin (Protein)


Gene name vapC Uniprot ID Q6N8B2
Locus tag TX73_RS10265 Protein ID WP_011157547.1
Coordinates 2243487..2243897 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag TX73_RS10270 Protein ID WP_011157548.1
Coordinates 2243894..2244157 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TX73_RS10250 (TX73_010250) 2239876..2240202 + 327 WP_011157544.1 hypothetical protein -
TX73_RS10255 (TX73_010255) 2240369..2242159 + 1791 WP_011157545.1 sulfatase-like hydrolase/transferase -
TX73_RS10260 (TX73_010260) 2242195..2243232 + 1038 WP_042441504.1 transporter -
TX73_RS10265 (TX73_010265) 2243487..2243897 - 411 WP_011157547.1 type II toxin-antitoxin system VapC family toxin Toxin
TX73_RS10270 (TX73_010270) 2243894..2244157 - 264 WP_011157548.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
TX73_RS10275 (TX73_010275) 2244338..2244763 + 426 WP_011157549.1 cupin domain-containing protein -
TX73_RS10280 (TX73_010280) 2244860..2246029 - 1170 WP_011157550.1 DUF2865 domain-containing protein -
TX73_RS10285 (TX73_010285) 2246215..2246523 - 309 WP_011157551.1 hypothetical protein -
TX73_RS10290 (TX73_010290) 2246924..2248315 + 1392 WP_011157552.1 cysteine--tRNA ligase -
TX73_RS10295 (TX73_010295) 2248312..2248848 + 537 WP_147408398.1 hypothetical protein -
TX73_RS10300 (TX73_010300) 2248845..2248976 + 132 WP_011157553.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-58)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15136.48 Da        Isoelectric Point: 5.6802

>T269254 WP_011157547.1 NZ_CP116810:c2243897-2243487 [Rhodopseudomonas palustris CGA009]
MSGWMLDTNVASHVIRGDRREIIERLVALPISDVVISSITEGELLYGLAKRGYPTALSERVREFLLRVDVLPWDHEVTKT
YADLRAVCEAKGVTLSPLDMMIAAHAAATNATLVTRDKAFSRVPSPLRIEDWAEMS

Download         Length: 411 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9888.91 Da        Isoelectric Point: 4.7969

>AT269254 WP_011157548.1 NZ_CP116810:c2244157-2243894 [Rhodopseudomonas palustris CGA009]
VTSRTAKIFTTGRSQAVRLPAEFRFEGSEVFVRRDPRTGDVILSRKPDSWDGLLQLHQSADVPDDFLGPSDRSQLPQDRD
PFEGWTE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N8B2

Antitoxin

Source ID Structure

References