Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 875758..876505 Replicon chromosome
Accession NZ_CP116807
Organism Mammaliicoccus lentus strain PVZ.22

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PN942_RS04355 Protein ID WP_269141993.1
Coordinates 875758..875892 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A178P7X5
Locus tag PN942_RS04360 Protein ID WP_016999960.1
Coordinates 875906..876505 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PN942_RS04345 (PN942_04340) 872499..874025 - 1527 WP_103269529.1 Ppx/GppA family phosphatase -
PN942_RS04350 (PN942_04345) 874109..875497 - 1389 WP_016999962.1 class II fumarate hydratase -
PN942_RS04355 (PN942_04350) 875758..875892 - 135 WP_269141993.1 SAS053 family protein Toxin
PN942_RS04360 (PN942_04355) 875906..876505 - 600 WP_016999960.1 hypothetical protein Antitoxin
PN942_RS04365 (PN942_04360) 876550..877704 - 1155 WP_016999959.1 N-acetylglucosamine-6-phosphate deacetylase -
PN942_RS04370 (PN942_04365) 877792..877932 + 141 WP_016999958.1 hypothetical protein -
PN942_RS04375 (PN942_04370) 877959..878432 - 474 WP_016999957.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PN942_RS04380 (PN942_04375) 878436..879563 - 1128 WP_016999956.1 tRNA epoxyqueuosine(34) reductase QueG -
PN942_RS04385 (PN942_04380) 879726..880487 - 762 WP_016999955.1 acetylglutamate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 5345.65 Da        Isoelectric Point: 3.8462

>T269252 WP_269141993.1 NZ_CP116807:c875892-875758 [Mammaliicoccus lentus]
MDKHIDHNENEEENEMVQDLEDVKELGKEMEQISEQNDEEKEEK

Download         Length: 135 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22222.10 Da        Isoelectric Point: 5.3603

>AT269252 WP_016999960.1 NZ_CP116807:c876505-875906 [Mammaliicoccus lentus]
MALNFKVFETKSIAARYAADIVRKQFNGDSTSVVGVHLNDENTTFFDELFDNVKKSPVNFSQIHVLDFDGKEDYYTELGV
PSKQVIKTDVGGDVESVIKDKVNTDKKKNKLMLNVLTLTDDSRIGLDYDSSIHPAREVVLLVTGKEKAKAVKQLYEEPAN
GSVDSAKLKQHRMVTVVLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A178P7X5

References