Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 448234..448887 Replicon chromosome
Accession NZ_CP116801
Organism Acinetobacter baumannii strain 37662RM2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PPK73_RS02185 Protein ID WP_000607077.1
Coordinates 448498..448887 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PPK73_RS02180 Protein ID WP_001288210.1
Coordinates 448234..448491 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPK73_RS02160 (PPK73_02160) 443750..444757 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
PPK73_RS02165 (PPK73_02165) 444776..445153 + 378 WP_001216380.1 50S ribosomal protein L17 -
PPK73_RS02170 (PPK73_02170) 445335..446825 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
PPK73_RS02175 (PPK73_02175) 446874..448046 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
PPK73_RS02180 (PPK73_02180) 448234..448491 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PPK73_RS02185 (PPK73_02185) 448498..448887 + 390 WP_000607077.1 membrane protein Toxin
PPK73_RS02190 (PPK73_02190) 449657..450742 + 1086 WP_261503124.1 hypothetical protein -
PPK73_RS02195 (PPK73_02195) 450820..451386 + 567 WP_000651538.1 rhombosortase -
PPK73_RS02200 (PPK73_02200) 451574..453769 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T269249 WP_000607077.1 NZ_CP116801:448498-448887 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT269249 WP_001288210.1 NZ_CP116801:448234-448491 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References