Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 6633402..6633907 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PKO50_RS30365 Protein ID WP_089392789.1
Coordinates 6633626..6633907 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PKO50_RS30360 Protein ID WP_089392790.1
Coordinates 6633402..6633629 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS30340 6630022..6630423 - 402 WP_275628080.1 GFA family protein -
PKO50_RS30345 6630435..6631165 - 731 Protein_5994 phytanoyl-CoA dioxygenase family protein -
PKO50_RS30350 6631162..6632088 - 927 WP_275628081.1 LysR family transcriptional regulator -
PKO50_RS30355 6632163..6633119 - 957 WP_275628082.1 agmatinase -
PKO50_RS30360 6633402..6633629 + 228 WP_089392790.1 CopG family ribbon-helix-helix protein Antitoxin
PKO50_RS30365 6633626..6633907 + 282 WP_089392789.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PKO50_RS30370 6634166..6634897 + 732 WP_275628083.1 RcnB family protein -
PKO50_RS30375 6634938..6635219 - 282 WP_109934375.1 DUF2218 domain-containing protein -
PKO50_RS30380 6635317..6636234 + 918 WP_275628084.1 LysR family transcriptional regulator -
PKO50_RS30385 6636293..6636748 + 456 WP_275628085.1 GNAT family N-acetyltransferase -
PKO50_RS30390 6636745..6637362 - 618 WP_275628086.1 DUF1826 domain-containing protein -
PKO50_RS30395 6637362..6638564 - 1203 WP_275628087.1 zinc metallochaperone GTPase ZigA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10269.77 Da        Isoelectric Point: 6.4614

>T269248 WP_089392789.1 NZ_CP116775:6633626-6633907 [Pseudomonas sp. 273]
MSLQWTHKAAADLDGLYDHYVVLIGPEKALKAVQDMVGQVKALADLSLSSVGRPSEVPGVRELPLERWPYQAAYRVKGRD
VQILRIDSVDNPG

Download         Length: 282 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8385.43 Da        Isoelectric Point: 6.6405

>AT269248 WP_089392790.1 NZ_CP116775:6633402-6633629 [Pseudomonas sp. 273]
MTTVISFRADDALARALDQLARATHRDRPYHLRQALAQYLERQSWHVAAIDEGLADANAGHLLPHAEIEAKWGLA

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References