269247

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 6117326..6117974 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag PKO50_RS28060 Protein ID WP_275630539.1
Coordinates 6117639..6117974 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag PKO50_RS28055 Protein ID WP_089392940.1
Coordinates 6117326..6117646 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS28045 6113289..6115067 - 1779 WP_109931745.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PKO50_RS28050 6115288..6117084 - 1797 WP_275627855.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PKO50_RS28055 6117326..6117646 - 321 WP_089392940.1 helix-turn-helix transcriptional regulator Antitoxin
PKO50_RS28060 6117639..6117974 - 336 WP_275630539.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PKO50_RS28065 6118181..6119986 - 1806 WP_109931741.1 phenylacyl-CoA dehydrogenase -
PKO50_RS28070 6120291..6120518 - 228 WP_089392938.1 hypothetical protein -
PKO50_RS28075 6120585..6121274 - 690 WP_275627856.1 dethiobiotin synthase -
PKO50_RS28080 6121354..6122160 - 807 WP_275627857.1 malonyl-ACP O-methyltransferase BioC -
PKO50_RS28085 6122153..6122878 - 726 WP_275627858.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(6-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12188.80 Da        Isoelectric Point: 6.6408

>T269247 WP_275630539.1 NZ_CP116775:c6117974-6117639 [Pseudomonas sp. 273]
MGSSKKDLLDMPEDVQDVFGFALHQAQEGGKHPQAKPMKGFSGAGVLEVVEDYDGDTYRAVYTVKLAAAVYALHCFQKKS
TRGIETPQHDIALIKKRLKDAEAHAKSVEND

Download         Length: 336 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11623.50 Da        Isoelectric Point: 10.2012

>AT269247 WP_089392940.1 NZ_CP116775:c6117646-6117326 [Pseudomonas sp. 273]
MIEFEEGSGNVYADLGRDDAGEMQVKARLASKIGSIIKARHLTQTQAAEILGLPQPKVSDMLRGKFRGISEAKMIDCLAR
LGRDVQIVVKAAPRSRREGRVEVVFA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References