Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 4532960..4533549 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PKO50_RS20580 Protein ID WP_089391624.1
Coordinates 4533193..4533549 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PKO50_RS20575 Protein ID WP_139210225.1
Coordinates 4532960..4533199 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS20550 4528196..4528819 + 624 WP_275627095.1 hypothetical protein -
PKO50_RS20555 4528853..4529560 + 708 WP_256595899.1 peptidoglycan-binding domain-containing protein -
PKO50_RS20560 4529575..4531200 + 1626 WP_275627096.1 hypothetical protein -
PKO50_RS20565 4531281..4532117 + 837 WP_275627097.1 AraC family transcriptional regulator -
PKO50_RS20570 4532169..4532774 + 606 WP_275627098.1 LysE family translocator -
PKO50_RS20575 4532960..4533199 + 240 WP_139210225.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PKO50_RS20580 4533193..4533549 + 357 WP_089391624.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PKO50_RS20585 4533892..4534701 - 810 WP_275627099.1 class I SAM-dependent methyltransferase -
PKO50_RS20590 4534793..4535386 - 594 WP_275627100.1 histidine phosphatase family protein -
PKO50_RS20595 4535630..4536058 - 429 WP_146219614.1 hypothetical protein -
PKO50_RS20600 4536479..4536832 + 354 WP_275627101.1 hypothetical protein -
PKO50_RS20605 4536844..4537938 - 1095 WP_275627102.1 D-alanine--D-alanine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(11-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13179.06 Da        Isoelectric Point: 7.3242

>T269243 WP_089391624.1 NZ_CP116775:4533193-4533549 [Pseudomonas sp. 273]
MVRRPPSVPDRGEIWHLQFDPSTGREMIGDHFCLVLSKREFNEIGLALVCPISQGTSSVARNQGFLVTLMGEGTDTQGNV
HSHQVRTLDWRARRAMFKEKAPDSVTNYVLSLVGAILE

Download         Length: 357 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8386.71 Da        Isoelectric Point: 5.6980

>AT269243 WP_139210225.1 NZ_CP116775:4532960-4533199 [Pseudomonas sp. 273]
MTTLALRKSGGSLIISVPAAFVAQNKLHAGSQVECNIVEGALVIKPMTRPSLAQLIAETPKDSLAPDWDNMQAVGAEQW

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References