269241

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2591966..2592519 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PKO50_RS12295 Protein ID WP_275629861.1
Coordinates 2592244..2592519 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PKO50_RS12290 Protein ID WP_089390469.1
Coordinates 2591966..2592244 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS12265 2587905..2589041 - 1137 WP_275629857.1 FMNH2-dependent alkanesulfonate monooxygenase -
PKO50_RS12270 2589347..2589646 - 300 WP_275629858.1 metalloregulator ArsR/SmtB family transcription factor -
PKO50_RS12275 2590302..2590805 + 504 WP_275629859.1 hypothetical protein -
PKO50_RS12280 2590874..2591503 - 630 WP_275629860.1 XRE family transcriptional regulator -
PKO50_RS12285 2591506..2591667 - 162 WP_177412081.1 hypothetical protein -
PKO50_RS12290 2591966..2592244 + 279 WP_089390469.1 ribbon-helix-helix domain-containing protein Antitoxin
PKO50_RS12295 2592244..2592519 + 276 WP_275629861.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PKO50_RS12300 2592568..2592993 + 426 WP_089390471.1 VOC family protein -
PKO50_RS12305 2593119..2593616 - 498 WP_275629862.1 RES domain-containing protein -
PKO50_RS12310 2593616..2594023 - 408 WP_275630468.1 DUF2384 domain-containing protein -
PKO50_RS12315 2594463..2595281 - 819 WP_275629863.1 protein phosphatase 2C domain-containing protein -
PKO50_RS12320 2595448..2596113 + 666 WP_109934960.1 M24 family metallopeptidase -
PKO50_RS12325 2596126..2596467 + 342 WP_109934959.1 gamma-glutamylcyclotransferase family protein -
PKO50_RS12330 2596576..2596731 + 156 Protein_2441 alcohol dehydrogenase -
PKO50_RS12335 2596919..2597263 + 345 WP_109934958.1 metalloregulator ArsR/SmtB family transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10590.19 Da        Isoelectric Point: 10.5619

>T269241 WP_275629861.1 NZ_CP116775:2592244-2592519 [Pseudomonas sp. 273]
MALQWTSKALSDLARFHEFLAPVNRSAAARTAQQLVAAPAVLLTNPRLGERLDEFVPRDVRRLLVGHYEMRYEIRGSDIH
LLRVWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10435.68 Da        Isoelectric Point: 4.6899

>AT269241 WP_089390469.1 NZ_CP116775:2591966-2592244 [Pseudomonas sp. 273]
MATTYKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWLDQEDERSRLTREALADVDAGRVIDHQSVQAWAESL
DSDTPLPLPVPR

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References