Detailed information of TA system TA269239

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 1258470..1259909
• Replicon: chromosome
• Accession: NZ_CP116775
• Organism: Pseudomonas sp. 273

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PKO50_RS06185
• Protein ID: WP_089393099.1
• Coordinates: 1258470..1259039 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PKO50_RS06190
• Protein ID: WP_275629137.1
• Coordinates: 1259049..1259909 (+)
• Length: 287 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PKO50_RS06180	1254739..1258218	-	3480	WP_275629136.1	hybrid sensor histidine kinase/response regulator	-
PKO50_RS06185	1258470..1259039	+	570	WP_089393099.1	GNAT family protein	Toxin
PKO50_RS06190	1259049..1259909	+	861	WP_275629137.1	AraC family transcriptional regulator	Antitoxin
PKO50_RS06195	1260374..1262248	+	1875	WP_275629138.1	MFS transporter	-
PKO50_RS06200	1262298..1262507	-	210	WP_009620558.1	cold-shock protein	-
PKO50_RS06205	1262702..1263016	-	315	WP_109936608.1	quaternary ammonium compound efflux SMR transporter SugE	-
PKO50_RS06210	1263156..1264100	-	945	WP_109936609.1	bile acid:sodium symporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-145)

Antitoxin

• DNA binding HTH domain, AraC-type (197-273)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21134.46 Da
• Isoelectric Point: 10.2630

>T269239 WP_089393099.1 NZ_CP116775:1258470-1259039 [Pseudomonas sp. 273]
MFRPSPITLQRGALRLEPMVEADVPELVALAEANREALRFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGALREGVLRNHRRLAG
GRLDDTVLYSITDLEWPQVKAALEAGFIG

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 287 a.a.
• Molecular weight: 31699.07 Da
• Isoelectric Point: 7.6358

>AT269239 WP_275629137.1 NZ_CP116775:1259049-1259909 [Pseudomonas sp. 273]
MPLDSAHGEQTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPTGSLVLINPDEVHTGS
KAHEAGWLYRGFYPEIEQVGSVLDELELGGRGLPTFDASVLHDAELSRAFLHVHRLLESNASSLERQTCWREALLLLFQR
YARVPEARPAGQEPLAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
APASVAAQLGYADQSHLSRQFKQAYGVAPGEYRLACGRSDMPAGNP

Nucleotide

• Length: 861 bp