Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1244071..1245210 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PKO50_RS06135 Protein ID WP_275629131.1
Coordinates 1244440..1245210 (+) Length 257 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1A5D9R9
Locus tag PKO50_RS06130 Protein ID WP_043271094.1
Coordinates 1244071..1244439 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS06095 1239256..1240091 - 836 Protein_1205 5'-nucleotidase, lipoprotein e(P4) family -
PKO50_RS06100 1240373..1241422 + 1050 WP_275629127.1 diguanylate cyclase -
PKO50_RS06105 1241410..1241781 - 372 WP_275629128.1 hypothetical protein -
PKO50_RS06110 1241857..1242198 - 342 WP_089393110.1 carboxymuconolactone decarboxylase family protein -
PKO50_RS06115 1242271..1242753 - 483 WP_109936595.1 GreA/GreB family elongation factor -
PKO50_RS06120 1242882..1243334 + 453 WP_275629129.1 hypothetical protein -
PKO50_RS06125 1243341..1243781 - 441 WP_275629130.1 RcnB family protein -
PKO50_RS06130 1244071..1244439 + 369 WP_043271094.1 DUF2384 domain-containing protein Antitoxin
PKO50_RS06135 1244440..1245210 + 771 WP_275629131.1 RES family NAD+ phosphorylase Toxin
PKO50_RS06140 1245286..1245492 + 207 WP_109936600.1 hypothetical protein -
PKO50_RS06145 1246019..1247383 + 1365 WP_275630427.1 DNA recombination protein RmuC -
PKO50_RS06150 1247712..1248599 - 888 WP_109936601.1 metal-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(69-212)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 257 a.a.        Molecular weight: 28882.02 Da        Isoelectric Point: 7.1070

>T269238 WP_275629131.1 NZ_CP116775:1244440-1245210 [Pseudomonas sp. 273]
MAPDVGAELWRECRGEQAIAPLRGKLVRLVESQEQVATLQLVDTLEEQALLEELIETSKPHLPPSSETLHYLLKTPFRYP
PLRWGSRFGRRHEPSLFYAALRLETAMAEGAYYRFVLWEGMASPPPSGRILSEHASFEARFQVQRGIRLQAPPFDRYAER
LQDPRDYHLSQALGSAMRAAAVEAFEYRSARCPEGGLNAALFVPSAFVDKRPRNLMPWLCETTADYVAFKHAQVPGAPRL
FPRAGFLVEGDLPHPA

Download         Length: 771 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13395.70 Da        Isoelectric Point: 10.8284

>AT269238 WP_043271094.1 NZ_CP116775:1244071-1244439 [Pseudomonas sp. 273]
MSALIRETPSADLVLAKAVLAAREQLGMTQQELAAIVGVDRSAVSRWKSGGLRVGSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTPNRHLSGVPLQRMEQVQGLVQVVEYLDAIRGKI

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1A5D9R9

References