269237

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 1237766..1238362 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag PKO50_RS06080 Protein ID WP_089393116.1
Coordinates 1238021..1238362 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag PKO50_RS06075 Protein ID WP_275629125.1
Coordinates 1237766..1238014 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS06045 1232995..1233552 - 558 WP_058072912.1 glycine cleavage system protein R -
PKO50_RS06050 1233724..1234602 + 879 WP_089393120.1 4-hydroxy-tetrahydrodipicolinate synthase -
PKO50_RS06055 1234615..1235811 + 1197 WP_089393119.1 outer membrane protein assembly factor BamC -
PKO50_RS06060 1235750..1236508 + 759 WP_089393118.1 MBL fold metallo-hydrolase -
PKO50_RS06065 1236540..1237250 + 711 WP_009620599.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
PKO50_RS06075 1237766..1238014 + 249 WP_275629125.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PKO50_RS06080 1238021..1238362 + 342 WP_089393116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PKO50_RS06085 1238440..1238736 - 297 WP_275629126.1 immunity protein Tsi6 family protein -
PKO50_RS06090 1238778..1238978 - 201 WP_139210215.1 hypothetical protein -
PKO50_RS06095 1239256..1240091 - 836 Protein_1205 5'-nucleotidase, lipoprotein e(P4) family -
PKO50_RS06100 1240373..1241422 + 1050 WP_275629127.1 diguanylate cyclase -
PKO50_RS06105 1241410..1241781 - 372 WP_275629128.1 hypothetical protein -
PKO50_RS06110 1241857..1242198 - 342 WP_089393110.1 carboxymuconolactone decarboxylase family protein -
PKO50_RS06115 1242271..1242753 - 483 WP_109936595.1 GreA/GreB family elongation factor -
PKO50_RS06120 1242882..1243334 + 453 WP_275629129.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1229633..1238993 9360


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12724.41 Da        Isoelectric Point: 4.8991

>T269237 WP_089393116.1 NZ_CP116775:1238021-1238362 [Pseudomonas sp. 273]
MTGLDVRFTETAAFSLQDQEDHLAEHHAAETAAAKIDALIDTILTKLQAAPVGYPVSRQASDFGITRYRELNHDGYRVFY
EVFERDKAIAVELVLRQKQDVEAALIRYCLIGI

Download         Length: 342 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9349.78 Da        Isoelectric Point: 8.9694

>AT269237 WP_275629125.1 NZ_CP116775:1237766-1238014 [Pseudomonas sp. 273]
MRVETISYLKRHAADLELDEPMVVTQNGVPTLVVESYAEHKRRDQAIALVKLLAMGSREYTEGKHCSVDELKARLAKRRA
QQ

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References