Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 147695..148362 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag PKO50_RS00695 Protein ID WP_275628534.1
Coordinates 147695..148105 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag PKO50_RS00700 Protein ID WP_089390172.1
Coordinates 148102..148362 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS00675 143834..144367 + 534 WP_089390167.1 (2Fe-2S)-binding protein -
PKO50_RS00680 144370..145611 + 1242 WP_275628531.1 cytochrome c -
PKO50_RS00685 145613..146581 + 969 WP_275628532.1 XdhC family protein -
PKO50_RS00690 146578..147153 + 576 WP_275628533.1 nucleotidyltransferase family protein -
PKO50_RS00695 147695..148105 - 411 WP_275628534.1 type II toxin-antitoxin system VapC family toxin Toxin
PKO50_RS00700 148102..148362 - 261 WP_089390172.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PKO50_RS00705 148447..149571 - 1125 WP_275628535.1 class I SAM-dependent methyltransferase -
PKO50_RS00710 149699..150475 + 777 WP_089390174.1 ferredoxin--NADP reductase -
PKO50_RS00715 150664..152217 + 1554 WP_275628536.1 TerC family protein -
PKO50_RS00720 152236..152649 - 414 WP_089390176.1 large-conductance mechanosensitive channel protein MscL -
PKO50_RS00725 152840..153082 + 243 WP_089390177.1 YdcH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

SpoVT-AbrB domain

(11-47)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15349.74 Da        Isoelectric Point: 8.2695

>T269234 WP_275628534.1 NZ_CP116775:c148105-147695 [Pseudomonas sp. 273]
VKYLLDTNILIYLLKNRPESVARRVNALPADAGLCMSFITYAELLKGAERSTRRGEVLRQLERLTRQVPVVYDGTPRLCE
HYAAQFTRLKLAGTPIGANGLWIACHALALEATLVTHNTREFERIDGLRLEDWAAE

Download         Length: 411 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9738.80 Da        Isoelectric Point: 4.2176

>AT269234 WP_089390172.1 NZ_CP116775:c148362-148102 [Pseudomonas sp. 273]
MSTSTLPSRVFMNGNSQAVRIPQEFRLDASRVEIHRQPNGDLVIHPLPEDRGEALLQALAGFDEDFVEALEEGQREQPPV
QEREEL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References