Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 122952..123526 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PKO50_RS00585 Protein ID WP_275628519.1
Coordinates 123161..123526 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PKO50_RS00580 Protein ID WP_089390284.1
Coordinates 122952..123167 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS00560 117963..118754 + 792 WP_275628516.1 taurine ABC transporter ATP-binding protein -
PKO50_RS00565 118744..119561 + 818 Protein_111 taurine ABC transporter permease TauC -
PKO50_RS00570 119743..120579 + 837 WP_275628517.1 taurine dioxygenase -
PKO50_RS00575 120859..122883 + 2025 WP_275628518.1 oligopeptide transporter, OPT family -
PKO50_RS00580 122952..123167 + 216 WP_089390284.1 CopG family transcriptional regulator Antitoxin
PKO50_RS00585 123161..123526 + 366 WP_275628519.1 type II toxin-antitoxin system VapC family toxin Toxin
PKO50_RS00590 123514..124239 - 726 WP_275628520.1 hypothetical protein -
PKO50_RS00595 124236..124418 - 183 WP_275628521.1 hypothetical protein -
PKO50_RS00600 124415..125563 - 1149 WP_275628522.1 PepSY domain-containing protein -
PKO50_RS00605 125571..127984 - 2414 Protein_119 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13329.35 Da        Isoelectric Point: 5.7101

>T269233 WP_275628519.1 NZ_CP116775:123161-123526 [Pseudomonas sp. 273]
MVKALFDTNILIDYLNGHEQARDELRRHDDPAISIVTWMEVMIGATPATAAATRAFLDSFALVPLDASVAERAVAVRQTL
RVKLPDAIIKASAEVQGRLLVSRNTRDFPVDDVGVRLPYSL

Download         Length: 366 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8061.01 Da        Isoelectric Point: 5.6663

>AT269233 WP_089390284.1 NZ_CP116775:122952-123167 [Pseudomonas sp. 273]
MRTLVDIPAEHLEALNALGEQQQQSRAALIREAVAEYLVRHRRQDAEAAFGLWNGSAGDGLAYQRKVREEW

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References