Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 482072..482616 Replicon chromosome
Accession NZ_CP116735
Organism Agrobacterium pusense strain CFBP5496

Toxin (Protein)


Gene name parE Uniprot ID A0A7W4TSM3
Locus tag CFBP5496_RS02405 Protein ID WP_072494055.1
Coordinates 482326..482616 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CFBP5496_RS02400 Protein ID WP_107341193.1
Coordinates 482072..482323 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5496_RS02375 (CFBP5496_0002375) 477170..477859 - 690 WP_037090773.1 HAD family hydrolase -
CFBP5496_RS02380 (CFBP5496_0002380) 478074..478754 + 681 WP_004440402.1 GntR family transcriptional regulator -
CFBP5496_RS02385 (CFBP5496_0002385) 478795..479256 + 462 WP_072494876.1 DUF1284 domain-containing protein -
CFBP5496_RS02390 (CFBP5496_0002390) 479216..480316 - 1101 WP_136882482.1 hypothetical protein -
CFBP5496_RS02395 (CFBP5496_0002395) 480553..481698 + 1146 WP_004440405.1 site-specific DNA-methyltransferase -
CFBP5496_RS02400 (CFBP5496_0002400) 482072..482323 + 252 WP_107341193.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CFBP5496_RS02405 (CFBP5496_0002405) 482326..482616 + 291 WP_072494055.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP5496_RS02410 (CFBP5496_0002410) 482648..483259 - 612 WP_022555751.1 HAD family phosphatase -
CFBP5496_RS02415 (CFBP5496_0002415) 483342..484451 - 1110 WP_052114204.1 A/G-specific adenine glycosylase -
CFBP5496_RS02420 (CFBP5496_0002420) 484364..484600 + 237 WP_162484560.1 hypothetical protein -
CFBP5496_RS02425 (CFBP5496_0002425) 484578..485042 + 465 WP_034495929.1 hypothetical protein -
CFBP5496_RS02430 (CFBP5496_0002430) 485070..485591 + 522 WP_037090771.1 DUF721 domain-containing protein -
CFBP5496_RS02435 (CFBP5496_0002435) 485720..486400 + 681 WP_037090769.1 DsbA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(8-62)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11196.72 Da        Isoelectric Point: 6.6456

>T269221 WP_072494055.1 NZ_CP116735:482326-482616 [Agrobacterium pusense]
MGFRLSLPAEEDVIRIAQEGIDLFGPQQARKYHRELFAIFDLISRNPRIARERGELSPSVRIHPFRAHLVVYRVEADDDV
LIVRVRHGHEDWGNEP

Download         Length: 291 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9300.50 Da        Isoelectric Point: 7.0134

>AT269221 WP_107341193.1 NZ_CP116735:482072-482323 [Agrobacterium pusense]
MVTMNISLPGQMKEWVEAQSKTGRYSNASDYVRDLIRKDQERSEKIAAMQGLVDEGLQAPSGHRSEDALFAEAEARSMKR
KIG

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W4TSM3

Antitoxin

Source ID Structure

References