Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 388352..389022 Replicon plasmid pAtFPH-AT4a
Accession NZ_CP116732
Organism Agrobacterium fabacearum strain FPH-AT4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6L23_RS24790 Protein ID WP_145166913.1
Coordinates 388603..389022 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F0LGD9
Locus tag G6L23_RS24785 Protein ID WP_003517203.1
Coordinates 388352..388606 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L23_RS24775 (G6L23_024775) 385820..386827 + 1008 WP_019565741.1 sensor histidine kinase -
G6L23_RS24780 (G6L23_024780) 387363..387968 - 606 WP_174048018.1 J domain-containing protein -
G6L23_RS24785 (G6L23_024785) 388352..388606 + 255 WP_003517203.1 plasmid stabilization protein Antitoxin
G6L23_RS24790 (G6L23_024790) 388603..389022 + 420 WP_145166913.1 type II toxin-antitoxin system VapC family toxin Toxin
G6L23_RS24795 (G6L23_024795) 389242..390138 - 897 WP_013637432.1 dihydrodipicolinate synthase family protein -
G6L23_RS24800 (G6L23_024800) 390171..391052 - 882 WP_111783761.1 SMP-30/gluconolactonase/LRE family protein -
G6L23_RS24805 (G6L23_024805) 391109..391828 - 720 WP_003517195.1 FCD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..735041 735041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15040.21 Da        Isoelectric Point: 5.1532

>T269218 WP_145166913.1 NZ_CP116732:388603-389022 [Agrobacterium fabacearum]
MILLDTNVISEPWKPVPDEAVIAWLDAQAVETLFISAITIAELRFGIAAMPSGRRQTILRDRLEGEVLPHFSGRILSFDL
TTSQFYSELMARTRASGKAIGTADGYIAATAAANGLTISTRDTSPFEAAGVKVINAWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9253.53 Da        Isoelectric Point: 8.9520

>AT269218 WP_003517203.1 NZ_CP116732:388352-388606 [Agrobacterium fabacearum]
MPAVTIRNLSEETHRALRVRAAHHGRSTEAEIRAIIEAAVRPPERIQLGSLLAAIGRDAELSNSDVEALQKSRDKTPAKP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0LGD9

References