Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 276698..277841 | Replicon | plasmid pAtFPH-AT4a |
| Accession | NZ_CP116732 | ||
| Organism | Agrobacterium fabacearum strain FPH-AT4 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | - |
| Locus tag | G6L23_RS24220 | Protein ID | WP_236772775.1 |
| Coordinates | 277302..277841 (+) | Length | 180 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | - |
| Locus tag | G6L23_RS24215 | Protein ID | WP_174047886.1 |
| Coordinates | 276698..277309 (+) | Length | 204 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G6L23_RS24205 (G6L23_024205) | 272129..273598 | - | 1470 | WP_174047885.1 | arginine-ornithine antiporter | - |
| G6L23_RS24210 (G6L23_024210) | 274060..275901 | + | 1842 | WP_174047906.1 | ATP-binding cassette domain-containing protein | - |
| G6L23_RS24215 (G6L23_024215) | 276698..277309 | + | 612 | WP_174047886.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
| G6L23_RS24220 (G6L23_024220) | 277302..277841 | + | 540 | WP_236772775.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| G6L23_RS24225 (G6L23_024225) | 278061..278255 | - | 195 | WP_236772776.1 | hypothetical protein | - |
| G6L23_RS24230 (G6L23_024230) | 278288..278829 | - | 542 | Protein_288 | IS6 family transposase | - |
| G6L23_RS24235 (G6L23_024235) | 278933..279829 | - | 897 | WP_174047888.1 | transglutaminase family protein | - |
| G6L23_RS24240 (G6L23_024240) | 280242..280625 | - | 384 | WP_174047889.1 | type II toxin-antitoxin system VapC family toxin | - |
| G6L23_RS24245 (G6L23_024245) | 280622..280822 | - | 201 | WP_013637280.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| G6L23_RS24250 (G6L23_024250) | 281115..281918 | - | 804 | WP_174047890.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..735041 | 735041 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 180 a.a. Molecular weight: 19779.82 Da Isoelectric Point: 6.4860
>T269216 WP_236772775.1 NZ_CP116732:277302-277841 [Agrobacterium fabacearum]
MAKAPANTPKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRYADFLGHG
DADPASLIADFGEIMAIESDDGLVFDINALAATVIREEIEYGGVRLKTAAYLKRTRIPITIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIA
MAKAPANTPKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRYADFLGHG
DADPASLIADFGEIMAIESDDGLVFDINALAATVIREEIEYGGVRLKTAAYLKRTRIPITIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIA
Download Length: 540 bp
Antitoxin
Download Length: 204 a.a. Molecular weight: 22188.71 Da Isoelectric Point: 10.5327
>AT269216 WP_174047886.1 NZ_CP116732:276698-277309 [Agrobacterium fabacearum]
MPSSQKAKLRSLLAARSMMRAHELREAGISAQTIARAVEGGEIERISRGVYQKRDAEVEENQILAEAIMRAPKGVIALVS
ALAFHGLTDQMPRRVWMAIGTSDWAPVQSYPPLRIVRFTESYLRQGIENQVIAGIDVPVYSIPKTLADLFRNPKLVDRSV
AVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALASNG
MPSSQKAKLRSLLAARSMMRAHELREAGISAQTIARAVEGGEIERISRGVYQKRDAEVEENQILAEAIMRAPKGVIALVS
ALAFHGLTDQMPRRVWMAIGTSDWAPVQSYPPLRIVRFTESYLRQGIENQVIAGIDVPVYSIPKTLADLFRNPKLVDRSV
AVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALASNG
Download Length: 612 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|