Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 131568..132115 Replicon plasmid pAtFPH-AT4a
Accession NZ_CP116732
Organism Agrobacterium fabacearum strain FPH-AT4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6L23_RS23460 Protein ID WP_174048025.1
Coordinates 131822..132115 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G6L23_RS23455 Protein ID WP_174048024.1
Coordinates 131568..131822 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L23_RS23425 (G6L23_023425) 126610..127098 + 489 WP_272479395.1 TetR/AcrR family transcriptional regulator -
G6L23_RS23430 (G6L23_023430) 127304..127615 + 312 WP_174047866.1 helix-turn-helix domain-containing protein -
G6L23_RS23435 (G6L23_023435) 127608..128861 + 1254 WP_272479406.1 HipA domain-containing protein -
G6L23_RS23440 (G6L23_023440) 129021..129335 - 315 WP_065689125.1 putative addiction module antidote protein -
G6L23_RS23445 (G6L23_023445) 129340..129636 - 297 Protein_131 type II toxin-antitoxin system RelE/ParE family toxin -
G6L23_RS23450 (G6L23_023450) 130163..131372 + 1210 Protein_132 Fic family protein -
G6L23_RS23455 (G6L23_023455) 131568..131822 + 255 WP_174048024.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6L23_RS23460 (G6L23_023460) 131822..132115 + 294 WP_174048025.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L23_RS23465 (G6L23_023465) 132200..133414 - 1215 WP_174048026.1 GGDEF domain-containing protein -
G6L23_RS23470 (G6L23_023470) 133586..133718 - 133 Protein_136 IS3 family transposase -
G6L23_RS23475 (G6L23_023475) 133839..134095 - 257 Protein_137 transposase -
G6L23_RS23480 (G6L23_023480) 134477..135472 - 996 WP_065662699.1 LacI family DNA-binding transcriptional regulator -
G6L23_RS23485 (G6L23_023485) 135648..136601 + 954 WP_019565640.1 sugar ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..735041 735041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11119.60 Da        Isoelectric Point: 6.1274

>T269214 WP_174048025.1 NZ_CP116732:131822-132115 [Agrobacterium fabacearum]
MPFSLSVQAEEDIISIAEEGIRIFGALVARQYHDEHFALLELIATNPRMARERHEISPSVRIHPFKAHPVVYRVTEDGSV
FVIRIRHGHEDWAGDSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9424.55 Da        Isoelectric Point: 8.5776

>AT269214 WP_174048024.1 NZ_CP116732:131568-131822 [Agrobacterium fabacearum]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSTEELFALATSRAEIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References