269213

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 318299..318761 Replicon chromosome
Accession NZ_CP116730
Organism Agrobacterium fabacearum strain FPH-AT4

Toxin (Protein)


Gene name pasB Uniprot ID A0A9E8LFT7
Locus tag G6L23_RS01500 Protein ID WP_065703878.1
Coordinates 318299..318550 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID F0L6V5
Locus tag G6L23_RS01505 Protein ID WP_013635548.1
Coordinates 318534..318761 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L23_RS01470 (G6L23_001470) 313337..314110 - 774 WP_065658316.1 L,D-transpeptidase -
G6L23_RS01475 (G6L23_001475) 314348..314977 + 630 WP_004432231.1 DNA-3-methyladenine glycosylase I -
G6L23_RS01480 (G6L23_001480) 314974..315417 + 444 WP_013635544.1 hypothetical protein -
G6L23_RS01485 (G6L23_001485) 315433..316476 - 1044 WP_174047382.1 YeiH family protein -
G6L23_RS01490 (G6L23_001490) 316559..317476 + 918 WP_004432220.1 LysR substrate-binding domain-containing protein -
G6L23_RS01495 (G6L23_001495) 317528..318292 - 765 WP_065703876.1 hypothetical protein -
G6L23_RS01500 (G6L23_001500) 318299..318550 - 252 WP_065703878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L23_RS01505 (G6L23_001505) 318534..318761 - 228 WP_013635548.1 DUF6290 family protein Antitoxin
G6L23_RS01510 (G6L23_001510) 318918..320543 + 1626 WP_065703880.1 histidine--tRNA ligase -
G6L23_RS01515 (G6L23_001515) 320548..320916 + 369 WP_026330619.1 VOC family protein -
G6L23_RS01520 (G6L23_001520) 320933..322060 + 1128 WP_004432209.1 ATP phosphoribosyltransferase regulatory subunit -
G6L23_RS01525 (G6L23_001525) 322057..322749 + 693 WP_174047383.1 ATP phosphoribosyltransferase -
G6L23_RS01530 (G6L23_001530) 322813..323259 - 447 WP_065703882.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-82)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9851.38 Da        Isoelectric Point: 9.5687

>T269213 WP_065703878.1 NZ_CP116730:c318550-318299 [Agrobacterium fabacearum]
VIWTIEYDVLVQKEMRKIDPQTRQRIRVAALDNPRQTGAALQGSELGSFWRYRVGDYRIICDIQDHKLVVLVVEIGHRRE
IYR

Download         Length: 252 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8909.92 Da        Isoelectric Point: 4.7254

>AT269213 WP_013635548.1 NZ_CP116730:c318761-318534 [Agrobacterium fabacearum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVVSAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0L6V5

References