Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-dinJ/YafQ-RelB |
Location | 114607..115138 | Replicon | plasmid unnamed1 |
Accession | NZ_CP116726 | ||
Organism | Pseudomonas aeruginosa strain 2881 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A2K4Y311 |
Locus tag | PMJ88_RS33925 | Protein ID | WP_023100672.1 |
Coordinates | 114857..115138 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | W2D9V6 |
Locus tag | PMJ88_RS33920 | Protein ID | WP_020303033.1 |
Coordinates | 114607..114870 (+) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PMJ88_RS33890 (PMJ88_33890) | 110301..110618 | + | 318 | WP_171947059.1 | hypothetical protein | - |
PMJ88_RS33895 (PMJ88_33895) | 110775..111272 | + | 498 | WP_023100668.1 | hypothetical protein | - |
PMJ88_RS33900 (PMJ88_33900) | 111265..111441 | + | 177 | WP_153549643.1 | hypothetical protein | - |
PMJ88_RS33905 (PMJ88_33905) | 111459..112817 | + | 1359 | WP_023100669.1 | replicative DNA helicase | - |
PMJ88_RS33910 (PMJ88_33910) | 112817..113308 | + | 492 | WP_023100670.1 | hypothetical protein | - |
PMJ88_RS33915 (PMJ88_33915) | 113540..114283 | + | 744 | WP_023100671.1 | glyoxalase superfamily protein | - |
PMJ88_RS33920 (PMJ88_33920) | 114607..114870 | + | 264 | WP_020303033.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
PMJ88_RS33925 (PMJ88_33925) | 114857..115138 | + | 282 | WP_023100672.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
PMJ88_RS33930 (PMJ88_33930) | 115175..115510 | + | 336 | WP_023100673.1 | hypothetical protein | - |
PMJ88_RS33935 (PMJ88_33935) | 115892..116344 | + | 453 | WP_023100674.1 | hypothetical protein | - |
PMJ88_RS33940 (PMJ88_33940) | 116393..117115 | - | 723 | WP_031634065.1 | hypothetical protein | - |
PMJ88_RS33945 (PMJ88_33945) | 117115..117465 | - | 351 | WP_023100676.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
PMJ88_RS33950 (PMJ88_33950) | 117462..117710 | - | 249 | WP_034017785.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
PMJ88_RS33955 (PMJ88_33955) | 117707..118126 | - | 420 | WP_057380713.1 | hypothetical protein | - |
PMJ88_RS33960 (PMJ88_33960) | 118200..118676 | - | 477 | WP_034026837.1 | single-stranded DNA-binding protein | - |
PMJ88_RS33965 (PMJ88_33965) | 118727..119125 | - | 399 | WP_176742248.1 | hypothetical protein | - |
PMJ88_RS33970 (PMJ88_33970) | 119134..119817 | - | 684 | WP_034018055.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..142661 | 142661 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10724.19 Da Isoelectric Point: 9.0277
>T269211 WP_023100672.1 NZ_CP116726:114857-115138 [Pseudomonas aeruginosa]
MRTIEQTSRFKRDYKREAKGPHRQTLASDFVAIVTALANDQPLAEKHRDHALNGDWKDHRDCHIKPDLVLIYRKPDDAVL
QLVRLGSHSELGL
MRTIEQTSRFKRDYKREAKGPHRQTLASDFVAIVTALANDQPLAEKHRDHALNGDWKDHRDCHIKPDLVLIYRKPDDAVL
QLVRLGSHSELGL
Download Length: 282 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2K4Y311 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0W0N2R7 |