Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4945701..4946959 | Replicon | chromosome |
Accession | NZ_CP116725 | ||
Organism | Pseudomonas aeruginosa strain 2881 |
Toxin (Protein)
Gene name | - | Uniprot ID | V6AJ34 |
Locus tag | PMJ88_RS23185 | Protein ID | WP_003086331.1 |
Coordinates | 4945701..4946456 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PMJ88_RS23190 | Protein ID | WP_003086329.1 |
Coordinates | 4946591..4946959 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PMJ88_RS23175 (PMJ88_23175) | 4940872..4943415 | + | 2544 | WP_033955245.1 | acyl-homoserine-lactone acylase QuiP | - |
PMJ88_RS23180 (PMJ88_23180) | 4943571..4944932 | - | 1362 | WP_003120632.1 | DNA recombination protein RmuC | - |
PMJ88_RS23185 (PMJ88_23185) | 4945701..4946456 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
PMJ88_RS23190 (PMJ88_23190) | 4946591..4946959 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PMJ88_RS23195 (PMJ88_23195) | 4947032..4948318 | - | 1287 | WP_003086327.1 | FAD-binding oxidoreductase | - |
PMJ88_RS23200 (PMJ88_23200) | 4948374..4949963 | - | 1590 | WP_023464367.1 | aldehyde dehydrogenase family protein | - |
PMJ88_RS23205 (PMJ88_23205) | 4950042..4950518 | + | 477 | WP_004353334.1 | elongation factor GreAB | - |
PMJ88_RS23210 (PMJ88_23210) | 4950521..4950796 | - | 276 | WP_023088486.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T269207 WP_003086331.1 NZ_CP116725:c4946456-4945701 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT269207 WP_003086329.1 NZ_CP116725:c4946959-4946591 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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